---
title: Can blood tests help identify which women have moderate-to-severe PMS?
description: Yes. Four blood markers related to inflammation were higher in women with moderate-to-severe PMS compared to mild PMS, and a combined score from these markers
url: https://niyora.com/research/papers/a-composite-hematological-inflammatory-panel-nlr-plr-mpv-crp-as-a-predictor-of-2026/
---

- [Niyora](https://niyora.com/)
- [Research](https://niyora.com/research/)
- [Library](https://niyora.com/research/library/)
- Can blood tests help identify which women have moderate-to-severe PMS?

Survey study, 2026

# Can blood tests help identify which women have moderate-to-severe PMS?

Yes. Four blood markers related to inflammation were higher in women with moderate-to-severe PMS compared to mild PMS, and a combined score from these markers predicted moderate-to-severe PMS.

 Early or limited evidence

80 women aged 18-40 with PMS

## What they did

Researchers enrolled 80 women aged 18-40 with PMS and tracked their symptom severity over two menstrual cycles. They divided women into mild PMS (32 women) and moderate-to-severe PMS (44 women) groups. During the late menstrual phase (days 21-28), they took blood samples and measured four markers related to inflammation and blood cells.

## What they found

All four blood markers were higher in women with moderate-to-severe PMS compared to mild PMS. A combined score from these markers correlated strongly with symptom severity scores and predicted which women had moderate-to-severe PMS.

## What it means for you

Blood tests might be a simple, cost-effective way to identify which women have moderate-to-severe PMS and need more intensive treatment. However, the study was small, done in one location, and the authors note that findings need to be tested in other populations before they can be widely used.

44

Moderate-to-severe PMS

32

Mild PMS

80

Women studied

## About the study

Original title A composite hematological inflammatory panel (NLR, PLR, MPV, CRP) as a predictor of moderate-to-severe Premenstrual Syndrome: A prospective observational study Authors T. Nischala, R Vel Murugan Journal International Journal of Drug Delivery Technology Year 2026 Study design Survey study Participants 44 What was tested None Open access Yes Read the paper [doi.org/10.25258/ijddt.16.50s.121](https://doi.org/10.25258/ijddt.16.50s.121)

## Topics

[Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)

Research tells you what helps on average. Niyora helps on the day it hits.

Calm down, see it another way, and decide what to say, with a PMS and PMDD app built by a doctor.

Ask AI about this page

Copy prompt

ChatGPT

↗

Claude

↗

Perplexity

↗

Google AI Mode

↗

Grok

↗