---
title: What are PMS and PMDD and what causes them? | Niyora
description: PMS causes mood, behavior, and physical symptoms before your period that resolve after menstruation. PMDD affects 5-8% of women and causes serious daily disru
url: https://niyora.com/research/papers/a-literature-review-on-premenstrual-syndrome-and-premenstrual-dysphoric-disorder-2025/
---

- [Niyora](https://niyora.com/)
- [Research](https://niyora.com/research/)
- [Library](https://niyora.com/research/library/)
- What are PMS and PMDD and what causes them?

Review, 2025

# What are PMS and PMDD and what causes them?

PMS causes mood, behavior, and physical symptoms before your period that resolve after menstruation. PMDD affects 5-8% of women and causes serious daily disruption. Cause is unknown but involves brain chemistry and hormone changes.

 Moderate study design

Literature review of PMS and PMDD across populations

## What they did

A literature review examining the causes, types, diagnosis, how common PMS and PMDD are, and how doctors treat them.

## What they found

PMS causes mood and behavior changes like irritability, tension, depression, and mood swings during the luteal phase of your cycle, along with physical symptoms like breast soreness and bloating. PMDD is a serious condition affecting 5-8% of women, many of whom also have severe PMS. Treatment usually involves a team approach with options including talk therapy, hormonal and non-hormonal drugs, and sometimes surgery.

## What it means for you

This summarizes what doctors know about PMS and PMDD but doesn't provide new research evidence for specific treatments. Doctors typically try multiple approaches rather than a single fix.

5-8%

Percentage of women with PMDD

## About the study

Original title A Literature Review on Premenstrual Syndrome and Premenstrual Dysphoric Disorder Authors Suvidha s. Mane Suvidha s. Mane, Lalita S. Karne, Omkar A. Devade et al. Journal Research Journal of Pharmacology and Pharmacodynamics Year 2025 Study design Review What was tested None Read the paper [doi.org/10.52711/2321-5836.2025.00007](https://doi.org/10.52711/2321-5836.2025.00007)

## Topics

[Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Premenstrual dysphoric disorder (PMDD)](https://niyora.com/research/topics/condition-pmdd/)[Menstrual cycle and mood](https://niyora.com/research/topics/condition-cycle-mood/)[Low mood and depression](https://niyora.com/research/topics/symptom-depression-mood/)

Research tells you what helps on average. Niyora helps on the day it hits.

Calm down, see it another way, and decide what to say, with a PMS and PMDD app built by a doctor.

## Related studies

Cohort study, 2026

What genetic factors are linked to premenstrual symptoms?

Study, 2026

How do women with PMDD process emotions differently in their brains?

Systematic review, 2026

Why do some women experience mood changes linked to their menstrual cycle?

Case-control study, 2026

Do women with PMS handle emotions differently at different times of the cycle?

Systematic review, 2025

Do people with PMDD and severe PMS have difficulties with emotion regulation?

Cohort study, 2025

Do women with a history of PMS or PMDD have more depression during pregnancy and after birth?

Ask AI about this page

Copy prompt

ChatGPT

↗

Claude

↗

Perplexity

↗

Google AI Mode

↗

Grok

↗