---
title: Do vitamin B6 and vitamin E help reduce PMS symptoms? | Niyora
description: Yes. Both vitamin B6 and vitamin E significantly reduced PMS symptoms compared to placebo. The two vitamins were equally effective with no significant differe
url: https://niyora.com/research/papers/a-prospective-randomised-trial-to-study-the-efficacy-of-vitamin-b6-pyridoxine-2017/
---

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- Do vitamin B6 and vitamin E help reduce PMS symptoms?

Randomised trial, 2017

# Do vitamin B6 and vitamin E help reduce PMS symptoms?

Yes. Both vitamin B6 and vitamin E significantly reduced PMS symptoms compared to placebo. The two vitamins were equally effective with no significant difference between them.

 Moderate study design

Women aged 17-25 with PMS symptoms

## What they did

90 women aged 17-25 with PMS symptoms were randomly assigned to three groups of 30. One group took vitamin E, one took vitamin B6, and one took placebo. The study measured symptom changes over time.

## What they found

Vitamin E and B6 groups both showed significant reduction in symptom scores compared to placebo. The improvement in the two vitamin groups was similar, with no significant difference between them.

## What it means for you

Vitamin B6 and E appear helpful for PMS symptoms, though the study does not specify what doses or how long women took the vitamins, which limits how we can use this information in practice.

90

women in study

30

women in each group

## About the study

Original title A Prospective Randomised Trial to Study the Efficacy of Vitamin B6 (Pyridoxine) and Vitamin E in Patients of Premenstrual Syndrome Authors Shikha Singh, Rekh Rani, As ha et al. Journal International Journal of Current Research and Academic Review Year 2017 Study design Randomised trial Participants 90 What was tested Vitamin B6 and vitamin E Open access Yes Read the paper [doi.org/10.20546/ijcrar.2017.509.003](https://doi.org/10.20546/ijcrar.2017.509.003)

## Topics

[Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Vitamin B6](https://niyora.com/research/topics/treatment-vitamin-b6/)[Vitamin E](https://niyora.com/research/topics/treatment-vitamin-e/)

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