--- title: Is PMDD associated with postpartum depression in first-time mothers? description: Yes, strongly. Women who developed postpartum depression were much more likely to have PMDD: 81.81% of women with depression had PMDD versus 16% without depre url: https://niyora.com/research/papers/association-between-postpartum-depression-and-premenstrual-dysphoric-disorder-in-2021/ --- - [Niyora](https://niyora.com/) - [Research](https://niyora.com/research/) - [Library](https://niyora.com/research/library/) - Is PMDD associated with postpartum depression in first-time mothers? Cohort study, 2021 # Is PMDD associated with postpartum depression in first-time mothers? Yes, strongly. Women who developed postpartum depression were much more likely to have PMDD: 81.81% of women with depression had PMDD versus 16% without depression. Early or limited evidence 72 first-time mothers in India having planned caesarean section ## What they did Prospective cohort study of 72 first-time mothers in India having planned caesarean section. Postpartum depression was screened at days 7, 14, and 42 after delivery using depression questionnaires. PMDD was assessed using DSM-5 criteria. ## What they found 30.55% of women developed postpartum depression. PMDD was present in 36.11% overall, but in 81.81% of women with postpartum depression versus 16% of women without it (p<0.0001). Marital satisfaction, planned pregnancy, and no family psychiatric history reduced postpartum depression risk. ## What it means for you Women with PMDD are at much higher risk of postpartum depression. Screening for PMDD could help identify pregnant women who need extra support after delivery. Main limits: very small sample, single location in India, included only women having planned caesarean. 72 Women followed 30.55 Percentage who developed postpartum depression <0.0001 P-value for PMDD difference ## About the study Original title Association between Postpartum Depression and Premenstrual Dysphoric Disorder in Primigravida after Elective Caesarean Section: A Prospective Cohort Study Authors Shyamal Dasgupta, Archi Ghanti, Chiranjit Ghosh et al. Journal JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH Year 2021 Study design Cohort study Participants 26 What was tested None (observational study) Open access Yes Read the paper [doi.org/10.7860/jcdr/2021/50211.15593](https://doi.org/10.7860/jcdr/2021/50211.15593) ## Topics [Premenstrual dysphoric disorder (PMDD)](https://niyora.com/research/topics/condition-pmdd/)[Low mood and depression](https://niyora.com/research/topics/symptom-depression-mood/)[Pregnancy and postpartum](https://niyora.com/research/topics/comorbidity-postpartum/)[Students and academic performance](https://niyora.com/research/topics/life-area-education/) Research tells you what helps on average. Niyora helps on the day it hits. Calm down, see it another way, and decide what to say, with a PMS and PMDD app built by a doctor. ## Related studies Survey study, 2026 Are PMS and depression connected in nursing students? Systematic review, 2026 Why do some women experience mood changes linked to their menstrual cycle? Systematic review, 2025 How common are PMS, PMDD, and painful periods in nursing students, and do they affect their schooling? Cohort study, 2025 Do women with a history of PMS or PMDD have more depression during pregnancy and after birth? Case-control study, 2024 Do steroid hormone levels change differently across the menstrual cycle in women with PMDD? Review, 2023 What treatments help mental and physical health problems linked to the menstrual cycle? Ask AI about this page Copy prompt ChatGPT ↗ Claude ↗ Perplexity ↗ Google AI Mode ↗ Grok ↗