---
title: Do women with PMS have different blood sugar and insulin levels than healthy women?
description: Yes, women with PMS had significantly lower blood glucose and lower insulin resistance during both menstrual phases compared to healthy women, but this was a
url: https://niyora.com/research/papers/blood-glucose-levels-insulin-concentrations-and-insulin-resistance-in-healthy-2013/
---

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- Do women with PMS have different blood sugar and insulin levels than healthy women?

Survey study, 2013

# Do women with PMS have different blood sugar and insulin levels than healthy women?

Yes, women with PMS had significantly lower blood glucose and lower insulin resistance during both menstrual phases compared to healthy women, but this was a small study with unclear practical importance.

 Early or limited evidence

30 women with severe PMS and 30 healthy controls, all medical students in Iran

## What they did

Compared 30 medical students with severe PMS symptoms to 30 healthy age-matched medical students. Blood glucose, insulin, and insulin resistance were measured during the follicular and luteal phases of the menstrual cycle.

## What they found

Women with PMS had significantly lower blood glucose during both phases (p=0.011 in follicular phase, p<0.0001 in luteal phase) and lower insulin resistance in the luteal phase (p=0.0005) compared to controls.

## What it means for you

This suggests metabolism may differ in women with PMS, but it is a small study in a specific population (medical students in Iran) and does not show whether these differences affect health or symptoms.

30

women per group

p<0.0001

glucose difference (luteal)

p=0.0005

insulin resistance difference

## About the study

Original title Blood glucose levels, insulin concentrations, and insulin resistance in healthy women and women with premenstrual syndrome: a comparative study Authors Zarei S, Mosalanejad L, Ghobadifar MA Journal Clinical and experimental reproductive medicine Year 2013 Study design Survey study Participants 30 What was tested None Open access Yes Read the paper [doi.org/10.5653/cerm.2013.40.2.76](https://doi.org/10.5653/cerm.2013.40.2.76)

## Topics

[Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Cognition, concentration and memory](https://niyora.com/research/topics/symptom-cognition/)[Students and academic performance](https://niyora.com/research/topics/life-area-education/)

Research tells you what helps on average. Niyora helps on the day it hits.

Calm down, see it another way, and decide what to say, with a PMS and PMDD app built by a doctor.

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