---
title: Do women with severe breast pain and swelling have worse PMS symptoms?
description: Yes. Women with cyclic mastopathy reported more severe PMS symptoms, especially water retention and breast symptoms, as well as mood changes, behavior changes
url: https://niyora.com/research/papers/breast-health-and-associated-premenstrual-symptoms-in-women-with-severe-cyclic-1997/
---

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- Do women with severe breast pain and swelling have worse PMS symptoms?

Case-control study, 1997

# Do women with severe breast pain and swelling have worse PMS symptoms?

Yes. Women with cyclic mastopathy reported more severe PMS symptoms, especially water retention and breast symptoms, as well as mood changes, behavior changes, and concentration problems.

 Early or limited evidence

34 women with severe cyclic mastopathy and 29 women without breast symptoms

## What they did

Case-control study comparing 34 women with severe cyclic breast pain and swelling to 29 women without breast symptoms. Both groups tracked breast pain, swelling, and PMS symptoms for one menstrual cycle and reported past breast health.

## What they found

Women with cyclic mastopathy had more doctor visits for breast lumpiness, more mammograms, and more biopsies. PMS symptoms were significantly more severe in the cyclic mastopathy group, particularly water retention and breast symptoms (p<0.001), and also negative mood, behavior changes, and concentration problems (p<0.05).

## What it means for you

Severe breast pain and swelling appears connected to worse PMS symptoms. The study only tracked women for one cycle and included a small sample size.

34

women with severe cyclic breast pain and swelling

29

women without breast symptoms (controls)

1 cycle

duration of tracking

## About the study

Original title Breast health and associated premenstrual symptoms in women with severe cyclic mastopathy Authors Goodwin PJ, Miller A, Del Giudice ME et al. Journal American journal of obstetrics and gynecology Year 1997 Study design Case-control study Participants 34 What was tested None, observational study Read the paper [doi.org/10.1016/s0002-9378(97)70392-2](https://doi.org/10.1016/s0002-9378(97)70392-2)

## Topics

[Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Bloating, breast tenderness and physical symptoms](https://niyora.com/research/topics/symptom-physical-symptoms/)[Pain and headache](https://niyora.com/research/topics/symptom-pain/)

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