--- title: Do women with PMS have different gut bacteria? | Niyora description: Yes. Women with PMS have clearly different gut bacteria compared to women without PMS. They have much higher levels of certain bacteria, especially one called url: https://niyora.com/research/papers/characteristics-of-the-gut-microbiota-in-japanese-patients-with-premenstrual-2022/ --- - [Niyora](https://niyora.com/) - [Research](https://niyora.com/research/) - [Library](https://niyora.com/research/library/) - Do women with PMS have different gut bacteria? Study, 2022 # Do women with PMS have different gut bacteria? Yes. Women with PMS have clearly different gut bacteria compared to women without PMS. They have much higher levels of certain bacteria, especially one called Collinsella, approximately 4.5 times higher. Moderate study design 24 Japanese women with PMS and 144 healthy Japanese women ## What they did Researchers compared gut bacteria from stool samples of 24 Japanese women with PMS to 144 Japanese women without PMS, analyzing the bacterial composition. ## What they found The PMS group had clearly different gut bacteria compared to the control group. Three types of bacteria were higher in the PMS group: Collinsella (approximately 4.5 times higher than the control group), Bifidobacterium, and Blautia. Collinsella showed the strongest link to PMS in women aged 30-40 years. ## What it means for you The bacteria living in your gut may be related to PMS. Since diet affects gut bacteria, changing your diet might help improve PMS. However, we do not know whether these bacteria cause PMS or if PMS causes these bacterial changes. This was a relatively small study and needs to be confirmed with larger research. 24 women with PMS studied 144 healthy women (control group) ~4.5x Collinsella higher in PMS group ## About the study Original title Characteristics of the Gut Microbiota in Japanese Patients with Premenstrual Syndrome Authors Okuma K, Kono K, Otaka M et al. Journal International journal of women's health Year 2022 Study design Study Participants 144 What was tested None (observational study comparing PMS and control groups) Open access Yes Read the paper [doi.org/10.2147/ijwh.s377066](https://doi.org/10.2147/ijwh.s377066) ## Topics [Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Diet and nutrition](https://niyora.com/research/topics/treatment-diet/)[IBS and gut symptoms](https://niyora.com/research/topics/comorbidity-ibs-gi/) Research tells you what helps on average. Niyora helps on the day it hits. Calm down, see it another way, and decide what to say, with a PMS and PMDD app built by a doctor. ## Related studies Randomised trial, 2026 Does individualized nutrition therapy help women with PMS improve symptoms and health? Survey study, 2026 Does diet affect PMS differently depending on a woman's gut bacteria? Survey study, 2024 How do hormonal changes during the menstrual cycle affect gut health and mood? Survey study, 2023 Could gut bacteria and probiotics help with PMS and PMDD? Non-randomised trial, 2022 Does S-equol supplement help reduce premenstrual symptoms? Case-control study, 2019 Are zinc and copper levels linked to PMS in teenage girls? Ask AI about this page Copy prompt ChatGPT ↗ Claude ↗ Perplexity ↗ Google AI Mode ↗ Grok ↗