--- title: Does childhood asthma or allergies increase the risk of PMS or PMDD as an adult? description: Yes. Women who had asthma in childhood had 20% higher risk of PMS/PMDD as adults, and those with food allergy had 28% higher risk. url: https://niyora.com/research/papers/childhood-asthma-allergies-and-risk-of-premenstrual-disorders-in-young-adulthood-2023/ --- - [Niyora](https://niyora.com/) - [Research](https://niyora.com/research/) - [Library](https://niyora.com/research/library/) - Does childhood asthma or allergies increase the risk of PMS or PMDD as an adult? Cohort study, 2023 # Does childhood asthma or allergies increase the risk of PMS or PMDD as an adult? Yes. Women who had asthma in childhood had 20% higher risk of PMS/PMDD as adults, and those with food allergy had 28% higher risk. Moderate study design 6,524 girls in the Growing Up Today Study followed to mean age 25.7 years ## What they did Prospective cohort study of 6,524 girls in the Growing Up Today Study, followed from 1996 to 2013. Researchers assessed asthma and allergies before age 18 and evaluated premenstrual symptoms when participants were around age 25.7 years. ## What they found At mean age 25.7 years, 19.3% met criteria for PMDs. Girls with childhood asthma had risk ratio 1.20 (95% CI 1.07-1.34). Girls with food allergy had risk ratio 1.28 (95% CI 1.06-1.54). The association was stronger for probable PMDD than PMS. ## What it means for you Childhood inflammatory conditions like asthma and food allergy may be connected to adult PMS and PMDD, possibly through shared inflammation pathways. This was one country and one cohort, so results may not apply everywhere. 19.3% Proportion meeting PMD criteria at age 25.7 1.20 Risk ratio for asthma 1.28 Risk ratio for food allergy ## About the study Original title Childhood asthma, allergies and risk of premenstrual disorders in young adulthood Authors Yihui Yang, Tong Gong, Carlos A. Camargo et al. Journal Nature Mental Health Year 2023 Study design Cohort study Participants 6,524 Open access Yes Read the paper [doi.org/10.1038/s44220-023-00066-4](https://doi.org/10.1038/s44220-023-00066-4) Original abstract Abstract Emerging evidence suggests inflammation is involved in the development of premenstrual disorders (PMDs). We assessed whether childhood asthma and allergies, as inflammatory conditions that may share etiology with PMDs, are associated with risk of PMDs in adulthood. We conducted a prospective cohort study of 6,524 girls in the Growing Up Today Study between 1996 and 2013. Self- and mother-reported diagnoses of asthma and allergies before age 18 were assessed at baseline and updated multiple times during follow-up. Current premenstrual symptoms and cases of PMDs were evaluated using validated tools in 2013. Log-binomial and linear regressions were employed to assess the associations of asthma/allergies with PMDs and premenstrual symptoms ( z score), respectively. At a mean (s.d.) age of 25.7 (3.5) years, 19.3% of participants met the criteria for PMDs. Compared with girls free of asthma, those having asthma had an increased risk of PMDs (adjusted risk ratio (aRR) 1.20 [95% CI 1.07 to 1.34]) and increased symptom score ( β = 0.13 [95% CI 0.08 to 0.19]). Allergies were positively associated with PMDs (aRR 1.11 [95% CI 0.99 to 1.24]) and premenstrual symptoms ( β = 0.09 [95% CI 0.04 to 0.14]). Specifically, the association with PMDs was statistically significant for food allergy (aRR 1.28 [95% CI 1.06 to 1.54]). The associations between asthma/food allergy and PMDs appeared more pronounced for probable premenstrual dysphoric disorder than for premenstrual syndrome. The findings, which show that individuals with childhood asthma or food allergy are at increased risk of PMDs in adulthood, may provide important evidence for future mechanistic research into inflammation and PMDs. Reproduced under CC-BY. ## Topics [Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Premenstrual dysphoric disorder (PMDD)](https://niyora.com/research/topics/condition-pmdd/)[Adolescents and young people](https://niyora.com/research/topics/life-area-adolescents/) Research tells you what helps on average. Niyora helps on the day it hits. Calm down, see it another way, and decide what to say, with a PMS and PMDD app built by a doctor. ## Related studies Guideline, 2023 What treatments work for PMS and PMDD? Cohort study, 2022 Does body size during childhood affect the risk of premenstrual disorders later? Cohort study, 2021 Does when you start puberty affect your risk of premenstrual disorders as an adult? Systematic review, 2021 How common is PMDD among female students in Ethiopia? Systematic review, 2017 Does Vitex agnus castus help treat premenstrual syndrome? Randomised trial, 2009 Does longer sertraline treatment prevent PMS symptoms from returning? Ask AI about this page Copy prompt ChatGPT ↗ Claude ↗ Perplexity ↗ Google AI Mode ↗ Grok ↗