---
title: Could gum disease cause PMS and sleep problems? | Niyora
description: In one case, treating a woman's gum disease with dental cleaning relieved both her PMS symptoms and sleep problems, suggesting gum disease might contribute to
url: https://niyora.com/research/papers/chronic-periodontitis-as-an-etiology-of-sleep-disturbances-and-premenstrual-2007/
---

- [Niyora](https://niyora.com/)
- [Research](https://niyora.com/research/)
- [Library](https://niyora.com/research/library/)
- Could gum disease cause PMS and sleep problems?

Study, 2007

# Could gum disease cause PMS and sleep problems?

In one case, treating a woman's gum disease with dental cleaning relieved both her PMS symptoms and sleep problems, suggesting gum disease might contribute to these symptoms in some women.

 Early or limited evidence

One woman with gum disease, PMS, and sleep disturbances

## What they did

This is a case report describing a woman with gum disease (chronic periodontitis) who also had PMS and sleep disturbances. She received dental treatment called scaling and curettage.

## What they found

After the dental treatment, both the PMS and sleep disturbances disappeared. The abstract notes that 80% of women with PMS also experience sleep disturbances.

## What it means for you

While this case is interesting, it is only one person. This is not proof that gum disease causes PMS because many women with gum disease do not have PMS. Much more research is needed.

80%

of women with PMS experience sleep disturbances

## About the study

Original title Chronic periodontitis as an etiology of sleep disturbances and premenstrual syndrome (PMS) Authors Haryono Utomo Journal Dental Journal (Majalah Kedokteran Gigi) Year 2007 Study design Study What was tested Dental treatment: scaling and curettage Open access Yes Read the paper [doi.org/10.20473/j.djmkg.v40.i1.p27-32](https://doi.org/10.20473/j.djmkg.v40.i1.p27-32) Original abstract

It is obvious that sleep disturbances may induced by acute pulpal or periodontal pain. Other causes of sleep disturbances which also termed as sleep dysfunction, or insomnia, according to the patient has to be treated by physician. Nevertheless, in a case report, surprisingly, periodontal treatment relieved sleep disturbances and premenstrual syndrome (PMS). Coincidentally, women also more vulnerable to sleep disturbances and periodontal disease. It is also interesting that the exact etiology of PMS is still unknown, and 80% women who suffered from PMS also experience sleep disturbances. Recently, there has been increasing numbers of literatures and evidence-based cases linking periodontal disease to systemic diseases. However, systemic effects of periodontal disease that lead to PMS which associated with sleep disturbances are rarely discussed. Several mechanisms had been proposed to involve in these symptoms: female sexual hormonal imbalance, stimulation of the hypothalamic-pituitary-adrenal axis (HPA-axis) and neurogenic switching mechanism. In addition, as estrogen makes women more susceptible to stress, it worsen the symptoms. The glucocorticoid hormones synthesized upon stimulation of the HPA-axis, either by stress or pro-inflammatory cytokines, may disrupt the sleep-wake cycle; and also create estrogen dominance. The aim of this study is to propose the etiopathogenesis of PMS which associated with sleep disturbances that may be related to chronic periodontitis. Since in this case report scaling and curettage resulted in the disappearing of PMS and sleep disturbances; the conclusion is that chronic periodontal disease may act as one of the etiologies of PMS and sleep disturbance.

Reproduced under CC-BY-SA.

## Topics

[Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Sleep and insomnia](https://niyora.com/research/topics/symptom-sleep/)[Stress](https://niyora.com/research/topics/symptom-stress/)

Research tells you what helps on average. Niyora helps on the day it hits.

Calm down, see it another way, and decide what to say, with a PMS and PMDD app built by a doctor.

## Related studies

Survey study, 2026

What dietary, lifestyle, and psychological factors are associated with PMS in young women?

Survey study, 2026

Does exercise help college women with period problems and mental health?

Survey study, 2026

Does fear of childbirth explain why women with PMS are more likely to develop postpartum depression?

Survey study, 2026

What factors most strongly drive PMS severity in female engineering students?

Survey study, 2025

Do menstrual problems and poor sleep affect mood and thinking in teenage girls?

Survey study, 2025

Can a smartphone app help diagnose and monitor PMS?

Ask AI about this page

Copy prompt

ChatGPT

↗

Claude

↗

Perplexity

↗

Google AI Mode

↗

Grok

↗
