--- title: Do women have different symptom patterns before, during, and after menopause? description: Yes. Women have different symptom patterns depending on whether they are before, during, or after menopause. All women experience fatigue, headache, anxiety, url: https://niyora.com/research/papers/clustering-of-145-000-symptom-logs-reveals-distinct-pre-peri-and-menopausal-2025/ --- - [Niyora](https://niyora.com/) - [Research](https://niyora.com/research/) - [Library](https://niyora.com/research/library/) - Do women have different symptom patterns before, during, and after menopause? Study, 2025 # Do women have different symptom patterns before, during, and after menopause? Yes. Women have different symptom patterns depending on whether they are before, during, or after menopause. All women experience fatigue, headache, anxiety, and brain fog regardless of life stage. Moderate study design 4789 women using the MenoLife app; 23% before menopause, 29% during transition, 48% after menopause ## What they did 4789 women used an app called MenoLife to track their symptoms every day. The researchers looked at 147,501 daily reports to find which symptoms clustered together and how they differed across women at different life stages. ## What they found Before menopause, women reported cramps, breast swelling, and mood problems. After menopause, women reported hot flashes, pain, and cognitive symptoms. During the transition, women had both types. Across all life stages, women reported fatigue, headache, anxiety, and brain fog. Hot flashes did not predict other symptoms except night sweats. ## What it means for you Treatments focused only on hot flashes or PMS miss much of what women experience. Fatigue, headache, anxiety, and brain fog occur across all reproductive life stages and need treatment. The study included women using one tracking app, which may not represent all women. 4789 women studied 147,501 daily symptom logs analyzed 45 different symptoms tracked ## About the study Original title Clustering of > 145,000 symptom logs reveals distinct pre, peri, and menopausal phenotypes Authors Aras SG, Grant AD, Konhilas JP Journal Scientific reports Year 2025 Study design Study Participants 4,789 What was tested None Open access Yes Read the paper [doi.org/10.1038/s41598-024-84208-3](https://doi.org/10.1038/s41598-024-84208-3) ## Topics [Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Menstrual cycle and mood](https://niyora.com/research/topics/condition-cycle-mood/)[Anxiety and tension](https://niyora.com/research/topics/symptom-anxiety/)[Cognition, concentration and memory](https://niyora.com/research/topics/symptom-cognition/)[Fatigue and energy](https://niyora.com/research/topics/symptom-fatigue/)[Pain and headache](https://niyora.com/research/topics/symptom-pain/)[Apps and digital interventions](https://niyora.com/research/topics/treatment-digital-health/)[Perimenopause and menopause](https://niyora.com/research/topics/comorbidity-perimenopause/)[Work and productivity](https://niyora.com/research/topics/life-area-work/) Research tells you what helps on average. Niyora helps on the day it hits. Calm down, see it another way, and decide what to say, with a PMS and PMDD app built by a doctor. ## Related studies Survey study, 2025 Can a plant-based supplement reduce PMS symptoms? Survey study, 2021 Does the menstrual cycle affect women's ability to train and compete? Systematic review, 2021 Does damask rose help reduce menstrual pain, headache, fatigue, anxiety, and bloating? Study, 2026 What are premenstrual syndrome and premenstrual dysphoric disorder? Survey study, 2025 How do personality traits like neuroticism affect PMS severity and sexual satisfaction? Lab study, 2023 Does sleep change across the menstrual cycle? Ask AI about this page Copy prompt ChatGPT ↗ Claude ↗ Perplexity ↗ Google AI Mode ↗ Grok ↗