---
title: Which PMDD medication is most cost-effective? | Niyora
description: This analysis suggests the birth control pill DRSP/EE may be the most cost-effective option for PMDD treatment, though fluoxetine could be cost-effective depe
url: https://niyora.com/research/papers/cost-effectiveness-analysis-of-treatments-for-premenstrual-dysphoric-disorder-2010/
---

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- Which PMDD medication is most cost-effective?

Study, 2010

# Which PMDD medication is most cost-effective?

This analysis suggests the birth control pill DRSP/EE may be the most cost-effective option for PMDD treatment, though fluoxetine could be cost-effective depending on how much someone is willing to spend.

 Early or limited evidence

This is an economic analysis based on published studies and cost data, not a direct study of women

## What they did

Researchers used a mathematical model to compare costs and treatment success of four FDA-approved PMDD medications: fluoxetine, sertraline, paroxetine, and DRSP/EE. They looked at medication costs, doctor visit costs, and how many women improved at 6 months based on published studies.

## What they found

Starting with DRSP/EE was more cost-effective than sertraline or paroxetine. Compared to fluoxetine, DRSP/EE was less expensive overall, though fluoxetine could be the better value depending on someone's budget for treatment success.

## What it means for you

This analysis used cost estimates from 2007 and treatment success rates from published studies, not new testing of these medications. Real-world costs and how well they work today might differ. This can help inform treatment choices when cost matters, but women respond differently.

4

medications compared

6 months

time measured for treatment success

## About the study

Original title Cost-effectiveness analysis of treatments for premenstrual dysphoric disorder Authors Rendas-Baum R, Yang M, Gricar J et al. Journal Applied health economics and health policy Year 2010 Study design Study Read the paper [doi.org/10.2165/11532210-000000000-00000](https://doi.org/10.2165/11532210-000000000-00000)

## Topics

[Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Premenstrual dysphoric disorder (PMDD)](https://niyora.com/research/topics/condition-pmdd/)[Low mood and depression](https://niyora.com/research/topics/symptom-depression-mood/)[SSRIs and antidepressants](https://niyora.com/research/topics/treatment-ssri/)[Oral contraceptives and drospirenone](https://niyora.com/research/topics/treatment-hormonal-contraceptives/)[Economic burden](https://niyora.com/research/topics/life-area-economic-burden/)

Research tells you what helps on average. Niyora helps on the day it hits.

Calm down, see it another way, and decide what to say, with a PMS and PMDD app built by a doctor.

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