--- title: Does curcumin reduce depression, anxiety, and stress in women with PMS and dysmenorrhea? description: Yes, curcumin significantly reduced depression, anxiety, and stress and improved mental health and quality of life compared to placebo. This was a larger, hig url: https://niyora.com/research/papers/curcumin-ameliorates-depression-and-anxiety-in-patients-with-premenstrual-2024/ --- - [Niyora](https://niyora.com/) - [Research](https://niyora.com/research/) - [Library](https://niyora.com/research/library/) - Does curcumin reduce depression, anxiety, and stress in women with PMS and dysmenorrhea? Randomised trial, 2024 # Does curcumin reduce depression, anxiety, and stress in women with PMS and dysmenorrhea? Yes, curcumin significantly reduced depression, anxiety, and stress and improved mental health and quality of life compared to placebo. This was a larger, high-quality study. Strong study design 128 women with premenstrual syndrome and dysmenorrhea ## What they did Triple-blinded randomized controlled trial with 128 women with PMS and dysmenorrhea. Participants took curcumin capsules (500 mg curcuminoids plus 5 mg piperine) or placebo daily for 3 consecutive menstrual cycles. Depression, anxiety, stress, and quality of life were measured before and after. ## What they found Curcumin significantly improved overall quality of life and mental health domain compared to placebo. It also significantly decreased depression, anxiety, and stress scores across all domains (p less than 0.05). ## What it means for you Curcumin is a natural, accessible option for reducing psychological symptoms and improving quality of life in women with PMS and dysmenorrhea. This was a larger, strong study, but more research is needed in different populations and settings. 128 Total women studied 500 Curcuminoids dose in milligrams 3 Number of menstrual cycles ## About the study Original title Curcumin Ameliorates Depression, and Anxiety in Patients with Premenstrual Syndrome and Dysmenorrhea: A Triple-Blinded Placebo-Controlled Trial Authors Afsane Bahrami, Fatemeh Nikoomanesh, Hossein Dehghani et al. Journal Nāmah-ʼi Dāniškadah-ʼi piziškī-i Irān. Year 2024 Study design Randomised trial Participants 64 What was tested Curcumin (500 mg curcuminoids plus 5 mg piperine) or placebo daily for 3 menstrual cycles Open access Yes Read the paper [doi.org/10.61186/jambr.32.152.174](https://doi.org/10.61186/jambr.32.152.174) ## Topics [Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Menstrual cycle and mood](https://niyora.com/research/topics/condition-cycle-mood/)[Dysmenorrhea and period pain](https://niyora.com/research/topics/condition-dysmenorrhea/)[Low mood and depression](https://niyora.com/research/topics/symptom-depression-mood/)[Anxiety and tension](https://niyora.com/research/topics/symptom-anxiety/)[Stress](https://niyora.com/research/topics/symptom-stress/)[Curcumin and turmeric](https://niyora.com/research/topics/treatment-curcumin/) Research tells you what helps on average. Niyora helps on the day it hits. Calm down, see it another way, and decide what to say, with a PMS and PMDD app built by a doctor. ## Related studies Cohort study, 2025 How common is PMS in Chinese teenage girls, and what factors are linked to it? Survey study, 2023 Did COVID-19 infection and vaccination affect women's menstrual cycles and mental health? Survey study, 2026 Does exercise help college women with period problems and mental health? Survey study, 2025 Do menstrual problems and poor sleep affect mood and thinking in teenage girls? Survey study, 2024 Did COVID-19 stress cause changes in menstrual cycles? Survey study, 2023 How common are PMS, PMDD, anxiety, and depression in rural adolescent girls? Ask AI about this page Copy prompt ChatGPT ↗ Claude ↗ Perplexity ↗ Google AI Mode ↗ Grok ↗