---
title: Is drospirenone an effective ingredient in birth control pills for PMDD?
description: Birth control pills containing drospirenone appear safer and better tolerated than other low-dose pills for mood changes, acne, and severe PMS (PMDD), with si
url: https://niyora.com/research/papers/drospirenone-a-novel-progestin-2007/
---

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- Is drospirenone an effective ingredient in birth control pills for PMDD?

Review, 2007

# Is drospirenone an effective ingredient in birth control pills for PMDD?

Birth control pills containing drospirenone appear safer and better tolerated than other low-dose pills for mood changes, acne, and severe PMS (PMDD), with similar overall safety profiles.

 Early or limited evidence

Women taking oral contraceptives and hormone therapy (specific numbers not given)

## What they did

Review of drospirenone in combined oral contraceptives and hormone therapy, examining how well it works and how safe it is.

## What they found

Drospirenone has special properties that block androgen and mineral effects. Pills with drospirenone had similar effectiveness and safety to other low-dose pills but showed better tolerability, including less weight gain, better mood, clearer skin, and better treatment of PMDD.

## What it means for you

Drospirenone may be a better choice for women with PMDD and acne, but this is a review without new effectiveness numbers provided.

## About the study

Original title Drospirenone: a novel progestin Authors Rapkin AJ, Winer SA Journal Expert opinion on pharmacotherapy Year 2007 Study design Review What was tested Drospirenone-containing contraceptives and hormone therapy Read the paper [doi.org/10.1517/14656566.8.7.989](https://doi.org/10.1517/14656566.8.7.989)

## Topics

[Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Premenstrual dysphoric disorder (PMDD)](https://niyora.com/research/topics/condition-pmdd/)[Bloating, breast tenderness and physical symptoms](https://niyora.com/research/topics/symptom-physical-symptoms/)[Oral contraceptives and drospirenone](https://niyora.com/research/topics/treatment-hormonal-contraceptives/)[Estradiol, progesterone and hormone therapy](https://niyora.com/research/topics/treatment-hormone-therapy/)[Diuretics and other drugs](https://niyora.com/research/topics/treatment-diuretics-other-drugs/)[Perimenopause and menopause](https://niyora.com/research/topics/comorbidity-perimenopause/)

Research tells you what helps on average. Niyora helps on the day it hits.

Calm down, see it another way, and decide what to say, with a PMS and PMDD app built by a doctor.

## Related studies

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