--- title: Does melissa officinalis (a herbal remedy) help reduce PMS symptoms? description: Yes. Melissa officinalis significantly reduced PMS symptom scores in high school girls compared to placebo, with continued improvement over three months. url: https://niyora.com/research/papers/effect-of-melissa-officinalis-capsule-on-the-intensity-of-premenstrual-syndrome-2015/ --- - [Niyora](https://niyora.com/) - [Research](https://niyora.com/research/) - [Library](https://niyora.com/research/library/) - Does melissa officinalis (a herbal remedy) help reduce PMS symptoms? Randomised trial, 2015 # Does melissa officinalis (a herbal remedy) help reduce PMS symptoms? Yes. Melissa officinalis significantly reduced PMS symptom scores in high school girls compared to placebo, with continued improvement over three months. Moderate study design 100 high school girls in Iran (50 in intervention group, 50 in control group) ## What they did This was a double-blind randomized placebo-controlled trial. 100 high school girls were divided into two groups of 50 each. The intervention group received 1200 mg of melissa officinalis essence daily throughout their menstrual cycle for three consecutive cycles. The other group received placebo. PMS symptoms were measured before treatment and at 1, 2, and 3 months. ## What they found PMS intensity scores in the intervention group fell from 42.56 before treatment to 32.72 after one month, 30.02 after two months, and 13.90 after three months (P<0.001). Results showed a significant reduction in PMS symptoms (P < 0.001). ## What it means for you Melissa officinalis may help reduce PMS symptoms. The study was limited to high school girls in Iran, and the authors note that further investigation is needed before recommending routine use. 1200 mg melissa officinalis dose per day 42.56 to 13.90 PMS intensity score before and after 3 months P < 0.001 statistical significance ## About the study Original title Effect of Melissa officinalis Capsule on the Intensity of Premenstrual Syndrome Symptoms in High School Girl Students Authors Akbarzadeh M, Dehghani M, Moshfeghy Z et al. Journal Nursing and midwifery studies Year 2015 Study design Randomised trial Participants 50 What was tested 1200 mg melissa officinalis essence capsules daily for three consecutive menstrual cycles Open access Yes Read the paper [doi.org/10.17795/nmsjournal27001](https://doi.org/10.17795/nmsjournal27001) ## Topics [Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Other herbal medicine](https://niyora.com/research/topics/treatment-herbal-other/)[Students and academic performance](https://niyora.com/research/topics/life-area-education/)[Adolescents and young people](https://niyora.com/research/topics/life-area-adolescents/) Research tells you what helps on average. Niyora helps on the day it hits. Calm down, see it another way, and decide what to say, with a PMS and PMDD app built by a doctor. ## Related studies Randomised trial, 2017 Does lemon balm capsule or educational support work better for reducing PMS symptoms? Randomised trial, 2015 Does aerobic exercise or fennel reduce PMS symptoms? Non-randomised trial, 2026 Can ginger tea help reduce PMS symptoms in teenage girls? Non-randomised trial, 2024 Does lavender aromatherapy reduce anxiety during premenstrual syndrome in teenage girls? Survey study, 2022 What diet and stress factors are linked to PMS in teenage girls? Non-randomised trial, 2020 Do aerobic exercise and Vitex extract reduce PMS symptoms in teenage girls? Ask AI about this page Copy prompt ChatGPT ↗ Claude ↗ Perplexity ↗ Google AI Mode ↗ Grok ↗