--- title: Does the contraceptive pill Yasmin ease premenstrual symptoms? description: In this study, women reported fewer premenstrual symptoms like low mood, poor concentration and water retention after six months on Yasmin, but because there url: https://niyora.com/research/papers/efficacy-of-yasmin-in-premenstrual-symptoms-2007/ --- - [Niyora](https://niyora.com/) - [Research](https://niyora.com/research/) - [Library](https://niyora.com/research/library/) - Does the contraceptive pill Yasmin ease premenstrual symptoms? Non-randomised trial, 2007 # Does the contraceptive pill Yasmin ease premenstrual symptoms? In this study, women reported fewer premenstrual symptoms like low mood, poor concentration and water retention after six months on Yasmin, but because there was no comparison group, we cannot be fully sure the pill itself caused the improvement. Early or limited evidence 100 women who wanted oral contraception for at least 6 months. ## What they did An open-label study (everyone knew what they were taking, and there was no placebo group) gave 100 women who wanted contraception a pill containing drospirenone and ethinyl estradiol (Yasmin) for up to 6 monthly cycles. Symptoms were measured with a questionnaire (WHAQ) at the start and at each visit, across three phases of the cycle. ## What they found 92 of the 100 women completed the study. By cycle 6, in the premenstrual phase there were significant drops in scores for impaired concentration, water retention, negative mood, increased appetite, feeling of well-being, and unwanted hair changes. Similar improvements showed up at the menstrual phase for concentration, mood, well-being and hair changes, and well-being and hair changes improved consistently even after the period ended. ## What it means for you This suggests Yasmin may help with premenstrual symptoms in women who also want contraception, but since there was no control group and everyone knew they were taking the pill, we can't rule out that some of the improvement was due to expectation or the passage of time rather than the drug itself. 100 Women enrolled 92% Completed the study 6 cycles Treatment length ## About the study Original title Efficacy of Yasmin in premenstrual symptoms Authors Taneepanichskul S, Jaisamrarn U, Phupong V Journal Archives of gynecology and obstetrics Year 2007 Study design Non-randomised trial Participants 100 What was tested Yasmin, a contraceptive pill containing drospirenone and ethinyl estradiol, taken for 6 monthly cycles. Read the paper [doi.org/10.1007/s00404-006-0280-6](https://doi.org/10.1007/s00404-006-0280-6) ## Topics [Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Menstrual cycle and mood](https://niyora.com/research/topics/condition-cycle-mood/)[Cognition, concentration and memory](https://niyora.com/research/topics/symptom-cognition/)[Oral contraceptives and drospirenone](https://niyora.com/research/topics/treatment-hormonal-contraceptives/)[Quality of life and daily functioning](https://niyora.com/research/topics/life-area-quality-of-life/) Research tells you what helps on average. Niyora helps on the day it hits. Calm down, see it another way, and decide what to say, with a PMS and PMDD app built by a doctor. ## Related studies Cohort study, 2010 How do anxiety disorders differ across different life stages? Survey study, 2020 What symptoms best predict whether PMDD will seriously affect daily life? Review, 2015 What do we know about PMS and PMDD and how are they treated? Review, 2013 What treatments work best for PMDD? Review, 2009 What causes PMDD and what are the treatment options? Study, 2026 What treatments work for PMDD? Ask AI about this page Copy prompt ChatGPT ↗ Claude ↗ Perplexity ↗ Google AI Mode ↗ Grok ↗