---
title: Do vitamin D and E supplements reduce PMS symptoms? | Niyora
description: Yes. Both vitamin D and E significantly reduced PMS symptoms compared to placebo.
url: https://niyora.com/research/papers/evaluating-the-effects-of-vitamin-d-and-vitamin-e-supplement-on-premenstrual-2016/
---

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- Do vitamin D and E supplements reduce PMS symptoms?

Randomised trial, 2016

# Do vitamin D and E supplements reduce PMS symptoms?

Yes. Both vitamin D and E significantly reduced PMS symptoms compared to placebo.

 Moderate study design

86 women with PMS

## What they did

86 women with PMS were randomly divided into three groups. They first tracked their symptoms for 2 months. Then for 2 months, one group took 200 mg vitamin D daily, one took 100 mg vitamin E daily, and one took a placebo. Symptoms before and after were compared.

## What they found

Both vitamin D and vitamin E groups showed significant improvement in PMS symptoms compared to the placebo group (P less than 0.05).

## What it means for you

Vitamin D and E supplements appear to be effective and affordable for treating PMS. However, the abstract does not specify which symptoms improved most. The study was moderate-sized and properly controlled, so the evidence is reasonably good.

86

women in study

200 mg

daily vitamin D dose

100 mg

daily vitamin E dose

## About the study

Original title Evaluating the effects of vitamin D and vitamin E supplement on premenstrual syndrome: A randomized, double-blind, controlled trial Authors Dadkhah H, Ebrahimi E, Fathizadeh N Journal Iranian journal of nursing and midwifery research Year 2016 Study design Randomised trial Participants 2 What was tested 200 mg vitamin D daily, 100 mg vitamin E daily, or placebo for 2 months Open access Yes Read the paper [doi.org/10.4103/1735-9066.178237](https://doi.org/10.4103/1735-9066.178237)

## Topics

[Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Vitamin D](https://niyora.com/research/topics/treatment-vitamin-d/)[Vitamin E](https://niyora.com/research/topics/treatment-vitamin-e/)

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Calm down, see it another way, and decide what to say, with a PMS and PMDD app built by a doctor.

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