---
title: Does Neptune Krill Oil help with PMS and period pain? | Niyora
description: Yes, it significantly reduced PMS symptoms and period pain, and worked better than fish oil for managing overall PMS symptoms.
url: https://niyora.com/research/papers/evaluation-of-the-effects-of-neptune-krill-oil-on-the-management-of-premenstrual-2003/
---

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- Does Neptune Krill Oil help with PMS and period pain?

Randomised trial, 2003

# Does Neptune Krill Oil help with PMS and period pain?

Yes, it significantly reduced PMS symptoms and period pain, and worked better than fish oil for managing overall PMS symptoms.

 Moderate study design

70 women of reproductive age diagnosed with premenstrual syndrome

## What they did

70 women with PMS were randomly assigned to either Neptune Krill Oil or omega-3 fish oil for 3 months in a double-blind trial. Symptoms were assessed using a self-assessment questionnaire based on diagnostic criteria, and the number of painkillers used for period pain was recorded at baseline, 45 days, and 90 days.

## What they found

Women taking Neptune Krill Oil had statistically significant symptom improvement from baseline measured at 45 and 90 days (P less than 0.001). Within the krill oil group, the number of painkillers used for period pain decreased significantly over time. Women taking Neptune Krill Oil used significantly fewer painkillers than women on fish oil (P less than 0.03).

## What it means for you

Neptune Krill Oil appears to reduce both emotional and physical PMS symptoms and reduces the need for painkillers compared to fish oil. However, the study only included 70 women and lasted 3 months, so longer-term effects and effects in larger populations remain unknown.

70

patients with complete data

3

months treatment duration

P < 0.001

significance of symptom improvement

## About the study

Original title Evaluation of the effects of Neptune Krill Oil on the management of premenstrual syndrome and dysmenorrhea Authors Sampalis F, Bunea R, Pelland MF et al. Journal Alternative medicine review : a journal of clinical therapeutic Year 2003 Study design Randomised trial Participants 70 What was tested Neptune Krill Oil versus omega-3 fish oil for 3 months Read the paper [https://pubmed.ncbi.nlm.nih.gov/12777162/](https://pubmed.ncbi.nlm.nih.gov/12777162/)

## Topics

[Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Dysmenorrhea and period pain](https://niyora.com/research/topics/condition-dysmenorrhea/)[Omega-3 fatty acids](https://niyora.com/research/topics/treatment-omega-3/)

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