---
title: Do antidepressant levels change during your menstrual cycle? | Niyora
description: In these two women, antidepressant blood levels went up and down during the premenstrual part of their cycle.
url: https://niyora.com/research/papers/fluctuating-levels-of-antidepressants-premenstrually-1992/
---

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- Do antidepressant levels change during your menstrual cycle?

Study, 1992

# Do antidepressant levels change during your menstrual cycle?

In these two women, antidepressant blood levels went up and down during the premenstrual part of their cycle.

 Early or limited evidence

2 women

## What they did

Measured blood levels of antidepressants in two women throughout their menstrual cycles.

## What they found

Both women had fluctuating antidepressant levels during the premenstrual part of their cycle.

## What it means for you

Your menstrual cycle may affect how your body processes antidepressants. Main limit: only two women, so much more research is needed to understand this pattern.

2

Women studied

## About the study

Original title Fluctuating levels of antidepressants premenstrually Authors Susan E. Kimmel, L. Gonsalvcs, David D. Youngs et al. Journal Journal of Psychosomatic Obstetrics & Gynecology Year 1992 Study design Study What was tested Observation of antidepressant blood levels Read the paper [doi.org/10.3109/01674829209009200](https://doi.org/10.3109/01674829209009200)

## Topics

[Menstrual cycle and mood](https://niyora.com/research/topics/condition-cycle-mood/)[SSRIs and antidepressants](https://niyora.com/research/topics/treatment-ssri/)

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