---
title: Does heptaminol adenosine phosphate help PMS symptoms? | Niyora
description: The medication appeared to work much better than a reference product for pelvic pain and pain and heaviness in the lower limbs. Women tolerated it very well.
url: https://niyora.com/research/papers/heptaminol-adenosine-phosphate-and-the-premenstrual-syndrome-1985/
---

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- Does heptaminol adenosine phosphate help PMS symptoms?

Study, 1985

# Does heptaminol adenosine phosphate help PMS symptoms?

The medication appeared to work much better than a reference product for pelvic pain and pain and heaviness in the lower limbs. Women tolerated it very well.

 Early or limited evidence

45 women with PMS.

## What they did

45 women took either heptaminol adenosine phosphate (6 gelatine capsules per day) or a reference product for 2 menstrual cycles. The researchers and women knew who received which treatment.

## What they found

Heptaminol adenosine phosphate showed much better results than the reference product for pelvic pain and for pain and heaviness in the lower limbs. It also performed better in the overall assessment. Women tolerated the medication very well.

## What it means for you

This medication may help reduce certain types of pain in PMS. A major limitation is that the study was open-label, meaning both the women and researchers knew who got which treatment, which can affect the results.

45

women in the trial

6

capsules per day

2

menstrual cycles

## About the study

Original title [Heptaminol adenosine phosphate and the premenstrual syndrome] Authors Anglade JP Journal Revue francaise de gynecologie et d'obstetrique Year 1985 Study design Study Participants 45 What was tested Heptaminol adenosine phosphate (6 gelatine capsules per day for 2 cycles). Read the paper [https://pubmed.ncbi.nlm.nih.gov/4039462/](https://pubmed.ncbi.nlm.nih.gov/4039462/)

## Topics

[Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)

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