---
title: Is hysterectomy and ovary removal an effective treatment for severe PMS?
description: Yes, 96% of women were satisfied with the surgery and 93.6% reported complete resolution of PMS symptoms. However, this is major surgery requiring ongoing hor
url: https://niyora.com/research/papers/hysterectomy-and-bilateral-oophorectomy-for-severe-premenstrual-syndrome-2004/
---

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- Is hysterectomy and ovary removal an effective treatment for severe PMS?

Non-randomised trial, 2004

# Is hysterectomy and ovary removal an effective treatment for severe PMS?

Yes, 96% of women were satisfied with the surgery and 93.6% reported complete resolution of PMS symptoms. However, this is major surgery requiring ongoing hormone therapy and should only be considered for women with severe, treatment-resistant PMS.

 Early or limited evidence

47 women with severe PMS who underwent surgery; median age 42 years

## What they did

A retrospective case series where researchers interviewed 47 women who had undergone total abdominal hysterectomy with removal of both ovaries for severe PMS between 1994 and 2000. Women completed structured questionnaires about satisfaction and symptoms.

## What they found

Median age was 42 years. Women had suffered PMS for a mean of 9.68 years and received prior treatment for a mean of 3.57 years before surgery. After surgery: 96% were satisfied or very satisfied, 93.6% reported complete resolution of cyclical symptoms, and 93.6% continued hormone replacement therapy for a mean of 3.8 years post-operatively.

## What it means for you

This surgery is extremely effective for very severe PMS, but it's only suitable for women with long-standing, severe symptoms who have exhausted other options. All women continued hormone therapy afterward, and this was not a randomized study, so we cannot compare it directly to other treatments.

47

women who underwent surgery

96%

satisfied or very satisfied

93.6%

with complete symptom resolution

## About the study

Original title Hysterectomy and bilateral oophorectomy for severe premenstrual syndrome Authors Cronje WH, Vashisht A, Studd JW Journal Human reproduction (Oxford, England) Year 2004 Study design Non-randomised trial What was tested Total abdominal hysterectomy with removal of both ovaries, followed by hormone replacement therapy Read the paper [doi.org/10.1093/humrep/deh354](https://doi.org/10.1093/humrep/deh354)

## Topics

[Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[GnRH agonists and ovarian suppression](https://niyora.com/research/topics/treatment-gnrh/)[Estradiol, progesterone and hormone therapy](https://niyora.com/research/topics/treatment-hormone-therapy/)[Surgical menopause](https://niyora.com/research/topics/treatment-surgery/)

Research tells you what helps on average. Niyora helps on the day it hits.

Calm down, see it another way, and decide what to say, with a PMS and PMDD app built by a doctor.

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