--- title: Does a hormone-releasing IUD help women who cannot tolerate regular IUDs? description: Yes, a progesterone-releasing IUD reduced menstrual bleeding and discomfort more often than it increased them, and 76 per cent of women continued using it aft url: https://niyora.com/research/papers/intrauterine-progesterone-contraceptive-system-as-an-alternative-in-cases-where-1979/ --- - [Niyora](https://niyora.com/) - [Research](https://niyora.com/research/) - [Library](https://niyora.com/research/library/) - Does a hormone-releasing IUD help women who cannot tolerate regular IUDs? Study, 1979 # Does a hormone-releasing IUD help women who cannot tolerate regular IUDs? Yes, a progesterone-releasing IUD reduced menstrual bleeding and discomfort more often than it increased them, and 76 per cent of women continued using it after one year. Early or limited evidence 25 women unable to use regular non-hormonal IUDs ## What they did A progesterone-releasing IUD was given to 25 women who could not use regular IUDs. Menstrual bleeding, discomfort, and blood iron levels were monitored. ## What they found Menstrual bleeding decreased more often than it increased. Discomfort also decreased more often than it increased. Hemoglobin, hematocrit, and serum iron levels either stayed the same or increased. 76 per cent of women were still using the IUD after one year. ## What it means for you Progesterone IUDs can help women with painful periods or heavy bleeding who could not use regular IUDs. The study was small with no control group for comparison. 25 Women studied 76 per cent Continuing use after one year ## About the study Original title Intrauterine progesterone contraceptive system as an alternative in cases where conventional IUD's are unsuitable Authors Ylöstalo P, Rantakylä P, Järvinen PA et al. Journal Acta obstetricia et gynecologica Scandinavica Year 1979 Study design Study Participants 25 What was tested Progesterone-releasing IUD Read the paper [doi.org/10.3109/00016347909154049](https://doi.org/10.3109/00016347909154049) ## Topics [Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Dysmenorrhea and period pain](https://niyora.com/research/topics/condition-dysmenorrhea/) Research tells you what helps on average. Niyora helps on the day it hits. Calm down, see it another way, and decide what to say, with a PMS and PMDD app built by a doctor. ## Related studies Cohort study, 2026 Do sleep, exercise, and diet quality affect period pain, heavy bleeding, and PMS in midlife? Systematic review, 2026 Does saffron reduce PMS and period pain symptoms? Randomised trial, 2025 Do vitamin D and E supplements reduce menstrual pain and PMS symptoms? Systematic review, 2025 Does digital healthcare help manage period pain and PMS? Cohort study, 2025 How common is PMS in Chinese teenage girls, and what factors are linked to it? Systematic review, 2025 How common are PMS, PMDD, and painful periods in nursing students, and do they affect their schooling? Ask AI about this page Copy prompt ChatGPT ↗ Claude ↗ Perplexity ↗ Google AI Mode ↗ Grok ↗