--- title: Do antipsychotic medications help psychosis that only happens around menstruation? description: In this case, a 30-year-old woman had psychotic symptoms around her menstrual cycle. Despite trying three different antipsychotic medications at different dos url: https://niyora.com/research/papers/lack-of-efficacy-of-antipsychotics-on-premenstrual-psychosis-a-case-report-2012/ --- - [Niyora](https://niyora.com/) - [Research](https://niyora.com/research/) - [Library](https://niyora.com/research/library/) - Do antipsychotic medications help psychosis that only happens around menstruation? Case report, 2012 # Do antipsychotic medications help psychosis that only happens around menstruation? In this case, a 30-year-old woman had psychotic symptoms around her menstrual cycle. Despite trying three different antipsychotic medications at different doses over 10 years, her symptoms kept coming back on a menstrual cycle pattern. The medications did not prevent these episodes. Early or limited evidence One 30-year-old woman with psychosis linked to menstrual cycle ## What they did A case report of a 30-year-old woman diagnosed with schizophrenia 10 years earlier. She had been treated with haloperidone 20 mg per day, then long-term risperidone injections, then aripiprazole starting at 10 mg per day and increased to 20 mg per day. Her symptoms were tracked and documented over time. ## What they found Despite continuous treatment with antipsychotics, she frequently had auditory hallucinations, self-talking, and self-laughing. Her symptoms first appeared after her first menstrual period in elementary school and have followed her menstrual cycle. The symptoms came back around menstruation even while on medication. ## What it means for you Psychosis that follows the menstrual cycle pattern may be different from typical schizophrenia and may not respond to standard antipsychotic medications the way other forms do. This is one woman's experience over a long time. The authors suggest this might be a type of premenstrual syndrome rather than the usual psychotic disorders, which could mean different treatments may be needed. 10 years since diagnosis 3 different antipsychotics tried 20 mg highest aripiprazole dose ## About the study Original title Lack of Efficacy of Antipsychotics on Premenstrual Psychosis: A Case Report Authors Lee YT, Chou YH Journal Psychopharmacology bulletin Year 2012 Study design Case report What was tested Haloperidone 20 mg per day, risperidone injections (long-term), and aripiprazole 10-20 mg per day Open access Yes Read the paper [doi.org/10.64719/pb.4058](https://doi.org/10.64719/pb.4058) ## Topics [Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Menstrual psychosis](https://niyora.com/research/topics/condition-menstrual-psychosis/)[Schizophrenia and psychosis](https://niyora.com/research/topics/comorbidity-psychosis/)[Adolescents and young people](https://niyora.com/research/topics/life-area-adolescents/) Research tells you what helps on average. Niyora helps on the day it hits. Calm down, see it another way, and decide what to say, with a PMS and PMDD app built by a doctor. ## Related studies Case report, 2013 Can severe mood changes around a period be an early sign of bipolar disorder? Case report, 2003 What causes psychosis linked to the menstrual cycle in adolescents? Case report, 2023 What is menstrual psychosis? Case report, 2022 Can PMDD cause brief psychotic episodes in young adolescents? Case report, 2022 Can aripiprazole prevent menstrual psychosis? Case report, 2022 What is cyclic menstrual psychosis in adolescents? Ask AI about this page Copy prompt ChatGPT ↗ Claude ↗ Perplexity ↗ Google AI Mode ↗ Grok ↗