---
title: Are zinc and antioxidant levels different in women with PMS? | Niyora
description: Yes. Women with PMS have lower zinc and antioxidant levels than women without PMS. Antioxidant levels appear linked to diet, particularly intake of antioxidan
url: https://niyora.com/research/papers/low-serum-zinc-and-total-antioxidant-capacity-levels-in-individuals-with-2022/
---

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- Are zinc and antioxidant levels different in women with PMS?

Case-control study, 2022

# Are zinc and antioxidant levels different in women with PMS?

Yes. Women with PMS have lower zinc and antioxidant levels than women without PMS. Antioxidant levels appear linked to diet, particularly intake of antioxidant-rich foods.

 Moderate study design

110 university students aged 18-28 (48 with PMS, 62 without), mean age 20.3±1.9 years

## What they did

Researchers studied 110 university students aged 18-28 (48 with PMS, 62 without). They measured blood zinc and antioxidant levels and assessed diet using 24-hour dietary recall.

## What they found

Women with PMS had lower serum zinc (11.67±6.42 µmol/L vs. 28.04±31.40 µmol/L in those without PMS). They also had lower antioxidant capacity (1.47±0.10 vs. 1.60±0.42 mmol/L) and higher body mass index (23.73±3.44 vs. 22.30±2.71 kg/m²). Women with PMS had lower intake of fiber, omega-3 fats, and vitamins E, B1, B2, B6, C, folate, and magnesium. Antioxidant levels were positively linked to dietary antioxidant and omega-3 fat intake.

## What it means for you

Lower mineral and antioxidant levels in women with PMS appear linked to lower intake of certain nutrients in their diet. However, all participants were young university students, so findings may not apply to women of different ages.

11.67±6.42

serum zinc PMS (µmol/L)

28.04±31.40

serum zinc non-PMS (µmol/L)

20.3±1.9

mean age in years

## About the study

Original title Low serum zinc and total antioxidant capacity levels in individuals with premenstrual syndrome Authors Tuğba Küçükkasap Cömert, Duygu Ağagündüz, Özlem Muşlu et al. Journal Gulhane Medical Journal Year 2022 Study design Case-control study Participants 110 What was tested None - observational comparison of existing groups Open access Yes Read the paper [doi.org/10.4274/gulhane.galenos.2021.80299](https://doi.org/10.4274/gulhane.galenos.2021.80299)

## Topics

[Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Diet and nutrition](https://niyora.com/research/topics/treatment-diet/)[Magnesium](https://niyora.com/research/topics/treatment-magnesium/)[Vitamin B6](https://niyora.com/research/topics/treatment-vitamin-b6/)[Zinc and iron](https://niyora.com/research/topics/treatment-zinc-iron/)[Students and academic performance](https://niyora.com/research/topics/life-area-education/)

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