---
title: Do women with PMS have lower magnesium levels? | Niyora
description: Yes, women with PMS have lower magnesium in their red blood cells. This difference appears throughout the menstrual cycle, not just before the period.
url: https://niyora.com/research/papers/magnesium-measures-across-the-menstrual-cycle-in-premenstrual-syndrome-1994/
---

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- Do women with PMS have lower magnesium levels?

Cohort study, 1994

# Do women with PMS have lower magnesium levels?

Yes, women with PMS have lower magnesium in their red blood cells. This difference appears throughout the menstrual cycle, not just before the period.

 Early or limited evidence

26 women with confirmed PMS and 19 control women

## What they did

26 women with PMS and 19 control women had their blood magnesium measured several times across their menstrual cycle, including plasma, red blood cells, and other blood cells.

## What they found

Women with PMS had significantly lower magnesium concentrations in red blood cells and other blood cells at each measurement time.

## What it means for you

Women with PMS may have lower magnesium overall, but the study was small and did not test whether supplementing magnesium would help.

26

Women with PMS

19

Control women

## About the study

Original title Magnesium measures across the menstrual cycle in premenstrual syndrome Authors Rosenstein DL, Elin RJ, Hosseini JM et al. Journal Biological psychiatry Year 1994 Study design Cohort study Participants 26 What was tested None Read the paper [doi.org/10.1016/0006-3223(94)90103-1](https://doi.org/10.1016/0006-3223(94)90103-1)

## Topics

[Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Cognition, concentration and memory](https://niyora.com/research/topics/symptom-cognition/)[Magnesium](https://niyora.com/research/topics/treatment-magnesium/)

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