---
title: Can calcium and vitamin D help with PMS symptoms? | Niyora
description: Calcium supplementation effectively alleviates most mood and body-related PMS symptoms according to clinical trials, and women with PMS may have calcium regul
url: https://niyora.com/research/papers/micronutrients-and-the-premenstrual-syndrome-the-case-for-calcium-2000/
---

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- Can calcium and vitamin D help with PMS symptoms?

Review, 2000

# Can calcium and vitamin D help with PMS symptoms?

Calcium supplementation effectively alleviates most mood and body-related PMS symptoms according to clinical trials, and women with PMS may have calcium regulation problems. However, this review does not provide specific trial details.

 Moderate study design

Premenopausal women with PMS (review of multiple studies)

## What they did

Review of research on how micronutrients, especially calcium and vitamin D, relate to PMS symptoms and menstrual cycle changes.

## What they found

Calcium and vitamin D levels change during the menstrual cycle. Estrogen regulates calcium metabolism and absorption, causing these fluctuations. Clinical trials found calcium supplementation effectively alleviates the majority of mood and body symptoms in women with PMS. Women with PMS may have underlying calcium regulation problems with vitamin D deficiency.

## What it means for you

PMS may be related to how the body handles calcium, which changes with hormones. Calcium supplementation seems to help many women. The abstract does not provide specific trial numbers or effect sizes, so we cannot judge how strong the evidence is.

Millions

premenopausal women with PMS

Majority

of mood and body symptoms relieved by calcium

## About the study

Original title Micronutrients and the premenstrual syndrome: the case for calcium Authors Thys-Jacobs S Journal Journal of the American College of Nutrition Year 2000 Study design Review What was tested Calcium supplementation (reviewed, not tested in this article) Read the paper [doi.org/10.1080/07315724.2000.10718920](https://doi.org/10.1080/07315724.2000.10718920)

## Topics

[Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Low mood and depression](https://niyora.com/research/topics/symptom-depression-mood/)[Calcium](https://niyora.com/research/topics/treatment-calcium/)[Magnesium](https://niyora.com/research/topics/treatment-magnesium/)[Vitamin D](https://niyora.com/research/topics/treatment-vitamin-d/)[Thyroid disorders](https://niyora.com/research/topics/comorbidity-thyroid/)

Research tells you what helps on average. Niyora helps on the day it hits.

Calm down, see it another way, and decide what to say, with a PMS and PMDD app built by a doctor.

## Related studies

Study, 2025

Could taking a combination of vitamins and minerals help with PMS and PMDD symptoms?

Study, 2008

Does calcium and vitamin D deficiency cause PMS?

Cohort study, 2007

Is there something different about calcium and vitamin D levels in women with PMDD?

Systematic review, 2025

Do nutritional interventions help with emotional symptoms of PMS?

Review, 2011

What are PMS and PMDD, and how common are they?

Randomised trial, 2003

What treatments work for PMS and PMDD?

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