--- title: Do estrogen patches or gels help control PMS symptoms? | Niyora description: Estrogen patches and gels work by stopping ovulation and the hormone changes that cause PMS. However, the abstract does not provide results from the trials re url: https://niyora.com/research/papers/non-contraceptive-oestrogen-containing-preparations-for-controlling-symptoms-of-2017/ --- - [Niyora](https://niyora.com/) - [Research](https://niyora.com/research/) - [Library](https://niyora.com/research/library/) - Do estrogen patches or gels help control PMS symptoms? Systematic review, 2017 # Do estrogen patches or gels help control PMS symptoms? Estrogen patches and gels work by stopping ovulation and the hormone changes that cause PMS. However, the abstract does not provide results from the trials reviewed, so effectiveness cannot be assessed. Moderate study design Women of reproductive age with PMS ## What they did Systematic review of randomized trials comparing non-contraceptive estrogen preparations (patches, gels, or implants) versus placebo or other active treatments. Included women of reproductive age with PMS diagnosed by at least two prospective menstrual cycles. Searched multiple databases through March 2016. ## What they found Transdermal estradiol by patch, gel, or implant effectively stops ovulation and the cyclical hormonal changes that produce cyclical PMS symptoms. A seven-day course of progestin is required each month for endometrial protection. Results from the trials are not included in this abstract. ## What it means for you Estrogen preparations work by stopping ovulation and hormone fluctuations. The abstract is incomplete and does not show results from the reviewed trials, making it impossible to assess how effective this approach is or what side effects may occur. 7 days progestin course duration per month patches and gels estrogen delivery methods ## About the study Original title Non-contraceptive oestrogen-containing preparations for controlling symptoms of premenstrual syndrome Authors Naheed B, Kuiper JH, Uthman OA et al. Journal The Cochrane database of systematic reviews Year 2017 Study design Systematic review What was tested Non-contraceptive estrogen preparations versus placebo or active treatment Open access Yes Read the paper [doi.org/10.1002/14651858.cd010503.pub2](https://doi.org/10.1002/14651858.cd010503.pub2) ## Topics [Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Premenstrual dysphoric disorder (PMDD)](https://niyora.com/research/topics/condition-pmdd/)[Low mood and depression](https://niyora.com/research/topics/symptom-depression-mood/)[Bloating, breast tenderness and physical symptoms](https://niyora.com/research/topics/symptom-physical-symptoms/)[Oral contraceptives and drospirenone](https://niyora.com/research/topics/treatment-hormonal-contraceptives/)[Estradiol, progesterone and hormone therapy](https://niyora.com/research/topics/treatment-hormone-therapy/) Research tells you what helps on average. Niyora helps on the day it hits. Calm down, see it another way, and decide what to say, with a PMS and PMDD app built by a doctor. ## Related studies Randomised trial, 2003 What treatments work for PMS and PMDD? Systematic review, 2012 What medications work best for PMDD? Randomised trial, 2011 Does a birth control pill reduce negative emotions, food cravings, and water retention in women with PMDD? Review, 2009 What causes PMDD and what are the treatment options? Randomised trial, 2008 Does drospirenone with ethinyl estradiol birth control help PMDD? Randomised trial, 2007 Does drospirenone/ethinylestradiol birth control help PMDD symptoms? Ask AI about this page Copy prompt ChatGPT ↗ Claude ↗ Perplexity ↗ Google AI Mode ↗ Grok ↗