---
title: Can vitamin B6 supplements treat health conditions beyond nutritional deficiency?
description: Many conditions have been treated with B6, but there is little evidence from controlled trials that it actually works for them.
url: https://niyora.com/research/papers/non-nutritional-uses-of-vitamin-b6-1999/
---

- [Niyora](https://niyora.com/)
- [Research](https://niyora.com/research/)
- [Library](https://niyora.com/research/library/)
- Can vitamin B6 supplements treat health conditions beyond nutritional deficiency?

Review, 1999

# Can vitamin B6 supplements treat health conditions beyond nutritional deficiency?

Many conditions have been treated with B6, but there is little evidence from controlled trials that it actually works for them.

 Early or limited evidence

Not specified; this is a review of general research

## What they did

This was a review of research on how vitamin B6 is used to treat various health conditions. The authors examined both the theoretical reasons B6 might help and the actual evidence from controlled trials.

## What they found

B6 has been used to treat many different conditions. Some uses are based on theory about how B6 works; others were discovered by trial and error. However, there is little evidence from properly conducted controlled trials that B6 actually works for these uses. At very high intake levels, B6 can damage peripheral nerves.

## What it means for you

Although B6 is often used to treat many conditions, we don't have good research proof that it works. The main limit is that this is a review of existing evidence, not a new study, and it shows the evidence is weak.

## About the study

Original title Non-nutritional uses of vitamin B6 Authors Bender DA Journal The British journal of nutrition Year 1999 Study design Review What was tested Vitamin B6 supplements Open access Yes Read the paper [doi.org/10.1017/s0007114599000082](https://doi.org/10.1017/s0007114599000082)

## Topics

[Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Diet and nutrition](https://niyora.com/research/topics/treatment-diet/)[Vitamin B6](https://niyora.com/research/topics/treatment-vitamin-b6/)

Research tells you what helps on average. Niyora helps on the day it hits.

Calm down, see it another way, and decide what to say, with a PMS and PMDD app built by a doctor.

## Related studies

Systematic review, 2025

Do nutritional interventions help with emotional symptoms of PMS?

Systematic review, 2007

What treatments work for premenstrual syndrome?

Study, 2002

Which PMS treatments have good scientific evidence?

Randomised trial, 2000

Which dietary supplements help PMS?

Review, 2026

Can diet and nutrition help reduce PMS symptoms?

Review, 2025

Do yoga and dietary changes help with PMS symptoms?

Ask AI about this page

Copy prompt

ChatGPT

↗

Claude

↗

Perplexity

↗

Google AI Mode

↗

Grok

↗
