---
title: Which nutritional supplements help treat premenstrual syndrome?
description: Vitamin B6 at 40-100 mg twice daily is widely used for PMS, especially in milder cases. Evening primrose oil at 2-3 g per day shows encouraging early results.
url: https://niyora.com/research/papers/nutritional-approaches-to-the-treatment-of-premenstrual-syndrome-1983/
---

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- Which nutritional supplements help treat premenstrual syndrome?

Randomised trial, 1983

# Which nutritional supplements help treat premenstrual syndrome?

Vitamin B6 at 40-100 mg twice daily is widely used for PMS, especially in milder cases. Evening primrose oil at 2-3 g per day shows encouraging early results. Other nutritional approaches may help but are unlikely to provide complete relief alone.

 Early or limited evidence

Review paper, not original research

## What they did

This is a review paper that examined non-drug nutritional approaches to treating PMS, including their doses and how they work.

## What they found

Vitamin B6 (pyridoxine) at 40-100 mg twice daily is widely used to treat PMS in less severe cases. Evening primrose oil at 2-3 g per day (the source of gamma-linolenic acid) has shown encouraging preliminary results, though a double-blind placebo-controlled study was still in progress. Some evidence suggests allergies may worsen premenstrually, so avoiding trigger substances may help.

## What it means for you

Vitamin B6 and evening primrose oil are potential non-drug treatments for PMS, but evidence is still limited and more research is needed. Nutritional approaches alone are unlikely to provide complete relief, especially for severe PMS.

40-100 mg

Vitamin B6 dose, twice daily

2-3 g

Evening primrose oil per day

## About the study

Original title Nutritional Approaches to the Treatment of Premenstrual Syndrome Authors M. G. Brush Journal Nutrition and Health Year 1983 Study design Randomised trial What was tested Vitamin B6 at 40-100 mg twice daily and evening primrose oil at 2-3 g per day Read the paper [doi.org/10.1177/026010608300200410](https://doi.org/10.1177/026010608300200410)

## Topics

[Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Diet and nutrition](https://niyora.com/research/topics/treatment-diet/)[Vitamin B6](https://niyora.com/research/topics/treatment-vitamin-b6/)[Evening primrose oil](https://niyora.com/research/topics/treatment-evening-primrose/)

Research tells you what helps on average. Niyora helps on the day it hits.

Calm down, see it another way, and decide what to say, with a PMS and PMDD app built by a doctor.

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