---
title: Does olanzapine help premenstrual psychosis? | Niyora
description: One girl with recurrent premenstrual psychosis was successfully treated with olanzapine. This is one case of a very rare condition, so we need much more resea
url: https://niyora.com/research/papers/olanzapine-treatment-of-premenstrual-onset-psychosis-a-case-report-2013/
---

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- Does olanzapine help premenstrual psychosis?

Case report, 2013

# Does olanzapine help premenstrual psychosis?

One girl with recurrent premenstrual psychosis was successfully treated with olanzapine. This is one case of a very rare condition, so we need much more research.

 Early or limited evidence

One 17-year-old girl with recurrent premenstrual psychosis

## What they did

Doctors treated one 17-year-old girl who had psychotic episodes (hallucinations or delusions) that happened before her period each month. They gave her olanzapine, an antipsychotic medication.

## What they found

She was successfully treated with olanzapine (20 mg/day). Her psychotic symptoms resolved.

## What it means for you

This is one girl's experience. Premenstrual psychosis is very rare and we don't understand what causes it. It might actually be related to bipolar disorder or schizophrenia rather than a separate condition. This case suggests antipsychotics might help, but much more research is needed.

17 years old

age of girl

20 mg/day

olanzapine dose

## About the study

Original title Olanzapine treatment of premenstrual onset psychosis: a case report Authors Hu LY, Chen PM Journal General hospital psychiatry Year 2013 Study design Case report What was tested Olanzapine (an antipsychotic medication) Read the paper [doi.org/10.1016/j.genhosppsych.2012.05.012](https://doi.org/10.1016/j.genhosppsych.2012.05.012)

## Topics

[Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Premenstrual exacerbation (PME)](https://niyora.com/research/topics/condition-pme/)[Anxiolytics and other psychotropics](https://niyora.com/research/topics/treatment-anxiolytics/)[Bipolar disorder](https://niyora.com/research/topics/comorbidity-bipolar/)[Schizophrenia and psychosis](https://niyora.com/research/topics/comorbidity-psychosis/)

Research tells you what helps on average. Niyora helps on the day it hits.

Calm down, see it another way, and decide what to say, with a PMS and PMDD app built by a doctor.

## Related studies

Cohort study, 2011

Does premenstrual symptom worsening change how bipolar disorder develops over time?

Systematic review, 2022

Do mental health disorders get worse during the menstrual cycle?

Study, 2026

Do anxiety and depression get worse before your period if you already have a mental health condition?

Survey study, 2026

What is the true rate of PMDD, and does it worsen mental health conditions?

Review, 2025

How does the menstrual cycle affect psychiatric symptoms like depression and anxiety?

Case report, 2017

Can mood symptoms like mania and psychosis change across the menstrual cycle in bipolar disorder?

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