---
title: Does oxanamide help with premenstrual tension? | Niyora
description: Among 45 patients treated, 37 benefited from the medication, and 4 had mild side effects.
url: https://niyora.com/research/papers/oxanamide-adjunctive-use-of-a-new-tranquilizer-in-gynecology-1959/
---

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- Does oxanamide help with premenstrual tension?

Study, 1959

# Does oxanamide help with premenstrual tension?

Among 45 patients treated, 37 benefited from the medication, and 4 had mild side effects.

 Early or limited evidence

45 patients (mostly women) with premenstrual tension and menopause symptoms.

## What they did

Doctors gave oxanamide to 45 patients with various gynecologic conditions, mainly premenstrual tension and menopause. This was an early trial from 1959.

## What they found

37 of the 45 patients benefited. 4 patients had mild side effects.

## What it means for you

Most patients in this small, early trial improved, but this was not a controlled study, so we cannot be sure the improvement was from the medication. Side effects were uncommon. This is outdated research that would not meet modern standards.

45

patients treated

37

benefited

4

had mild side effects

## About the study

Original title Oxanamide; adjunctive use of a new tranquilizer in gynecology Authors WOODHULL RB Journal California medicine Year 1959 Study design Study Participants 45 What was tested Oxanamide, a tranquilizer. Read the paper [https://pubmed.ncbi.nlm.nih.gov/13638840/](https://pubmed.ncbi.nlm.nih.gov/13638840/)

## Topics

[Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Anxiety and tension](https://niyora.com/research/topics/symptom-anxiety/)[Anxiety disorders and OCD](https://niyora.com/research/topics/comorbidity-anxiety-disorders/)

Research tells you what helps on average. Niyora helps on the day it hits.

Calm down, see it another way, and decide what to say, with a PMS and PMDD app built by a doctor.

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