---
title: Can ozone therapy reduce PMS symptoms? | Niyora
description: In 5 women with PMS, inflammation markers decreased and infections were reduced with ozone therapy combined with diet changes. Women reported improvement.
url: https://niyora.com/research/papers/ozonoterapia-en-el-abordaje-integrativo-del-sindrome-premenstrual-reporte-de-2020/
---

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- Can ozone therapy reduce PMS symptoms?

Study, 2020

# Can ozone therapy reduce PMS symptoms?

In 5 women with PMS, inflammation markers decreased and infections were reduced with ozone therapy combined with diet changes. Women reported improvement.

 Early or limited evidence

5 women with PMS attending a clinic between October 2018 and August 2019

## What they did

5 women with PMS were treated with ozone therapy (rectal, uterine, and cervical applications) plus an anti-inflammatory diet and supplements between October 2018 and August 2019. Inflammation markers and infections in the genital area were measured at the start, middle, and end of treatment.

## What they found

Two inflammation markers in the uterus decreased in all 5 women (100%), indicating reduced inflammation and clinical improvement. Intestinal infections (Candida and gram-negative bacteria) found in the genital area were also reduced.

## What it means for you

This suggests ozone therapy might reduce uterine inflammation and infection. Main limitations: only 5 women studied, no comparison group, and the researchers say more trials are needed.

5

women treated

100%

showed decreased inflammation markers

## About the study

Original title Ozonoterapia en el abordaje integrativo del síndrome premenstrual. Reporte de casos Authors Alejandra Menassa de Lucía Journal Ozone Therapy Global Journal Year 2020 Study design Study Participants 5 What was tested Ozone therapy (rectal, uterine, and cervical applications) plus anti-inflammatory diet and supplements Open access Yes Read the paper [doi.org/10.67442/3dqce358](https://doi.org/10.67442/3dqce358)

## Topics

[Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[SSRIs and antidepressants](https://niyora.com/research/topics/treatment-ssri/)[Oral contraceptives and drospirenone](https://niyora.com/research/topics/treatment-hormonal-contraceptives/)[GnRH agonists and ovarian suppression](https://niyora.com/research/topics/treatment-gnrh/)[Diet and nutrition](https://niyora.com/research/topics/treatment-diet/)[Surgical menopause](https://niyora.com/research/topics/treatment-surgery/)

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Calm down, see it another way, and decide what to say, with a PMS and PMDD app built by a doctor.

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