---
title: Does how consistently you sleep during your cycle affect your metabolism?
description: Overall sleep variability was linked to lower insulin resistance. However, very short or very long sleep nights were linked to higher leptin and insulin level
url: https://niyora.com/research/papers/patterns-of-sleep-duration-and-metabolic-biomarkers-across-the-menstrual-cycle-2025/
---

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- Does how consistently you sleep during your cycle affect your metabolism?

Cohort study, 2025

# Does how consistently you sleep during your cycle affect your metabolism?

Overall sleep variability was linked to lower insulin resistance. However, very short or very long sleep nights were linked to higher leptin and insulin levels.

 Moderate study design

259 premenopausal women in New York, 2005-2007

## What they did

259 premenopausal women tracked daily sleep for 2 menstrual cycles. Blood tests for leptin, insulin, and glucose were done at 16 points timed to cycle phases.

## What they found

Sleep duration from 1 or 2 nights before blood tests was not linked to metabolic markers. But overall sleep variability was associated with lower insulin resistance. Extremely short or long sleep bouts were associated with higher leptin, insulin, and insulin resistance.

## What it means for you

How consistently you sleep during your cycle may affect insulin and energy storage. The study only tracked 2 cycles, so it is unclear if results apply long-term.

259

women

2

menstrual cycles tracked

16

biomarker assessment points

## About the study

Original title Patterns of Sleep Duration and Metabolic Biomarkers Across the Menstrual Cycle Authors Dunietz GL, Shedden K, Lyu X et al. Journal The Journal of clinical endocrinology and metabolism Year 2025 Study design Cohort study Participants 259 What was tested None Open access Yes Read the paper [doi.org/10.1210/clinem/dgae191](https://doi.org/10.1210/clinem/dgae191)

## Topics

[Sleep and insomnia](https://niyora.com/research/topics/symptom-sleep/)[Perimenopause and menopause](https://niyora.com/research/topics/comorbidity-perimenopause/)

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