---
title: Is premenstrual mood problems linked to depression disorder? | Niyora
description: Yes. Women with a history of depressive disorder were significantly more likely to have premenstrual mood symptoms. Women with other psychiatric disorders wer
url: https://niyora.com/research/papers/premenstrual-affective-syndrome-and-psychiatric-disorder-1976/
---

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- Is premenstrual mood problems linked to depression disorder?

Survey study, 1976

# Is premenstrual mood problems linked to depression disorder?

Yes. Women with a history of depressive disorder were significantly more likely to have premenstrual mood symptoms. Women with other psychiatric disorders were not.

 Early or limited evidence

81 women presenting to a neurology clinic with functional headache

## What they did

Cross-sectional study of 81 women presenting to a neurology clinic with functional headaches. Researchers examined the relationship between a history of depressive disorder and premenstrual mood symptoms.

## What they found

Premenstrual mood symptoms were significantly associated with a history of depressive disorder. Women with non-affective psychiatric disorders showed no greater frequency of premenstrual mood symptoms than psychiatrically normal women.

## What it means for you

If you have premenstrual mood symptoms, you might also have a depressive disorder. Limitation: all women in the study had headaches and were seen in a clinic, so results may not apply to all women.

81

women with functional headache

## About the study

Original title Premenstrual affective syndrome and psychiatric disorder Authors Kashiwagi T, McClure JN Jr, Wetzel RD Journal Diseases of the nervous system Year 1976 Study design Survey study Participants 81 What was tested None Read the paper [https://pubmed.ncbi.nlm.nih.gov/943281/](https://pubmed.ncbi.nlm.nih.gov/943281/)

## Topics

[Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Low mood and depression](https://niyora.com/research/topics/symptom-depression-mood/)[Pain and headache](https://niyora.com/research/topics/symptom-pain/)[Major depressive disorder](https://niyora.com/research/topics/comorbidity-major-depression/)[Relationships and partners](https://niyora.com/research/topics/life-area-relationships/)

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