--- title: What should doctors know about PMS and PMDD in teenagers? | Niyora description: PMS and PMDD are common in teenagers and affect school, friendships, and mental health because the body is overly sensitive to normal hormone changes. SSRIs ( url: https://niyora.com/research/papers/premenstrual-disorders-in-adolescents-an-interdisciplinary-perspective-2026/ --- - [Niyora](https://niyora.com/) - [Research](https://niyora.com/research/) - [Library](https://niyora.com/research/library/) - What should doctors know about PMS and PMDD in teenagers? Review, 2026 # What should doctors know about PMS and PMDD in teenagers? PMS and PMDD are common in teenagers and affect school, friendships, and mental health because the body is overly sensitive to normal hormone changes. SSRIs (antidepressants), birth control pills, exercise, therapy, and lifestyle changes can help, though most evidence comes from adult studies. Early or limited evidence Adolescents with premenstrual disorders (literature review) ## What they did A structured review of research on how premenstrual disorders develop, present, and can be treated in adolescents, with emphasis on adolescent-specific evidence. ## What they found PMS and PMDD affect school functioning, relationships, and psychological well-being in adolescents. Symptoms overlap with normal puberty and psychiatric disorders, making diagnosis challenging. SSRIs and combined oral contraceptives help, along with psychological, lifestyle, physical activity, and physiotherapy approaches. ## What it means for you Doctors should diagnose PMS and PMDD in teenagers by tracking symptoms over time and tailor treatment to their age. Main limitation: most treatment evidence comes from adult studies, not from adolescent-specific research. ## About the study Original title Premenstrual Disorders in Adolescents: An Interdisciplinary Perspective Authors Dobrzeniecki K, Kacprzak M, Stachecka D et al. Journal Journal of clinical medicine Year 2026 Study design Review What was tested SSRIs, combined oral contraceptives, psychological interventions, lifestyle changes, physical activity, physiotherapy Open access Yes Read the paper [doi.org/10.3390/jcm15187046](https://doi.org/10.3390/jcm15187046) Original abstract Background: Premenstrual disorders (PMDs), including premenstrual syndrome and premenstrual dysphoric disorder, are common conditions that may substantially affect adolescents' physical and psychological well-being. However, their presentation and management during adolescence are complicated by reproductive-axis maturation, overlap with other medical conditions, and limited adolescent-specific evidence. This review aimed to provide an interdisciplinary perspective on PMDs in adolescents, integrating biological, psychological, developmental, clinical, and sociocultural aspects. Methods: A structured narrative review was conducted. Publications addressing the neuroendocrine and developmental mechanisms, clinical manifestations, psychosocial consequences, diagnosis, and treatment of PMDs were considered, with adolescent-specific evidence prioritized where available. Results: Current evidence suggests that PMDs are associated with altered sensitivity to physiological ovarian steroid fluctuations and their neuroactive effects rather than abnormal circulating hormone concentrations alone. In adolescents, PMDs may present with diverse somatic, affective, cognitive, and behavioral symptoms and are associated with impaired quality of life, school functioning, interpersonal relationships, and psychological well-being. Diagnostic assessment remains challenging because symptoms may overlap with normal pubertal changes and psychiatric disorders. Prospective monitoring of symptom cyclicity and functional impairment is therefore essential. Pharmacological treatments, particularly selective serotonin reuptake inhibitors and selected combined oral contraceptives, represent important therapeutic options, while psychological, lifestyle, physical activity, and physiotherapeutic interventions may provide additional benefits. However, most treatment evidence is derived from adult populations. Conclusions: PMDs in adolescents should be conceptualized as multidimensional conditions requiring an interdisciplinary approach integrating gynecological, psychiatric, psychological, endocrinological, primary care, and lifestyle perspectives. Greater recognition and developmentally appropriate assessment may facilitate earlier diagnosis and individualized management. Further prospective, adolescent-specific research is needed to clarify the biological and psychosocial determinants of PMDs and establish evidence-based strategies for their multidisciplinary management. Reproduced under CC-BY. ## Topics [Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Premenstrual dysphoric disorder (PMDD)](https://niyora.com/research/topics/condition-pmdd/)[Low mood and depression](https://niyora.com/research/topics/symptom-depression-mood/)[Cognition, concentration and memory](https://niyora.com/research/topics/symptom-cognition/)[SSRIs and antidepressants](https://niyora.com/research/topics/treatment-ssri/)[Oral contraceptives and drospirenone](https://niyora.com/research/topics/treatment-hormonal-contraceptives/)[Relationships and partners](https://niyora.com/research/topics/life-area-relationships/)[Quality of life and daily functioning](https://niyora.com/research/topics/life-area-quality-of-life/)[Adolescents and young people](https://niyora.com/research/topics/life-area-adolescents/) Research tells you what helps on average. Niyora helps on the day it hits. Calm down, see it another way, and decide what to say, with a PMS and PMDD app built by a doctor. ## Related studies Study, 2022 What are the symptoms, causes, and treatments of PMS and PMDD? Study, 2008 How common is PMDD and how does it affect women's lives? Review, 2024 What are the most effective treatments for PMDD? Randomised trial, 2023 Does taking sertraline when PMDD symptoms start improve how well women function? Review, 2017 What causes PMDD and what are the best treatments? Review, 2015 What do we know about PMS and PMDD and how are they treated? Ask AI about this page Copy prompt ChatGPT ↗ Claude ↗ Perplexity ↗ Google AI Mode ↗ Grok ↗