---
title: Do premenstrual mood symptoms change during perimenopause? | Niyora
description: Yes, hormonal changes during early perimenopause may worsen premenstrual mood disorders in some women. Doctors should monitor women with PMDD as they approach
url: https://niyora.com/research/papers/premenstrual-mood-symptoms-in-the-perimenopause-2021/
---

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- Do premenstrual mood symptoms change during perimenopause?

Review, 2021

# Do premenstrual mood symptoms change during perimenopause?

Yes, hormonal changes during early perimenopause may worsen premenstrual mood disorders in some women. Doctors should monitor women with PMDD as they approach midlife for worsening symptoms.

 Early or limited evidence

Reviews research on premenstrual mood disorders in perimenopause

## What they did

A review of recent research on how reproductive aging affects premenstrual mood disorders like PMDD and how treatment may need to change as women approach midlife.

## What they found

Early menopause transition brings hormonal changes that may worsen existing mood disorders. Some women experience depression from rising hormones, while others become more sensitive to hormone withdrawal in late perimenopause and early postmenopause.

## What it means for you

Women with PMDD or premenstrual mood disorders may experience worse symptoms during perimenopause and need closer medical monitoring during this time. More research is needed to understand how these symptoms change as women age.

## About the study

Original title Premenstrual Mood Symptoms in the Perimenopause Authors Sander B, Gordon JL Journal Current psychiatry reports Year 2021 Study design Review What was tested None. This is a literature review discussing treatment adjustments. Read the paper [doi.org/10.1007/s11920-021-01285-1](https://doi.org/10.1007/s11920-021-01285-1)

## Topics

[Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Premenstrual dysphoric disorder (PMDD)](https://niyora.com/research/topics/condition-pmdd/)[Low mood and depression](https://niyora.com/research/topics/symptom-depression-mood/)[Perimenopause and menopause](https://niyora.com/research/topics/comorbidity-perimenopause/)

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