--- title: Do women with premenstrual tension have different hormone patterns? description: Yes. Women with premenstrual tension had measurable differences in their hormone patterns compared to women without the condition. url: https://niyora.com/research/papers/premenstrual-tension-hormonal-profiles-1984/ --- - [Niyora](https://niyora.com/) - [Research](https://niyora.com/research/) - [Library](https://niyora.com/research/library/) - Do women with premenstrual tension have different hormone patterns? Study, 1984 # Do women with premenstrual tension have different hormone patterns? Yes. Women with premenstrual tension had measurable differences in their hormone patterns compared to women without the condition. Moderate study design 30 women with premenstrual tension (19 with premenstrual syndrome and 11 with menstrual distress) ## What they did They measured urinary oestrogen and pregnanediol daily throughout the menstrual cycle in 30 women with premenstrual tension (19 with premenstrual syndrome and 11 with menstrual distress). They compared results to 86 controls and a subset matched for age and parity. ## What they found The women with premenstrual tension had significantly lower pregnanediol values during both the follicular and luteal phases. The rise in pregnanediol occurred later than normal compared to the pre-ovulatory oestrogen peak. They also had lower than normal pre-ovulatory peak oestrogen and either very high or very low oestrogen values in the luteal phase. Other abnormalities included anovulatory cycles (no ovulation) and short luteal phases. ## What it means for you Women with premenstrual tension have measurable hormone abnormalities that suggest real biological differences in how their ovaries function. The main limits are the small sample size and that this describes what is different but does not explain what causes these differences or how to treat them based on these findings. 30 Women with premenstrual tension studied 86 Control women without the condition 116 Total women (30 patients plus 86 controls) ## About the study Original title Premenstrual Tension-Hormonal Profiles Authors Lorraine Dennerstein, C. Spencer-Gardner, J. B. Brown et al. Journal Journal of Psychosomatic Obstetrics & Gynecology Year 1984 Study design Study Participants 30 What was tested None - observational hormone measurement study Read the paper [doi.org/10.3109/01674828409023851](https://doi.org/10.3109/01674828409023851) ## Topics [Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Anxiety and tension](https://niyora.com/research/topics/symptom-anxiety/)[Pregnancy and postpartum](https://niyora.com/research/topics/comorbidity-postpartum/) Research tells you what helps on average. Niyora helps on the day it hits. Calm down, see it another way, and decide what to say, with a PMS and PMDD app built by a doctor. ## Related studies Review, 2003 How do menstrual cycle hormones affect the brain and cause mood disorders like PMDD? Randomised trial, 2017 Does Sepranolone reduce symptoms of severe premenstrual syndrome (PMDD)? Cohort study, 2015 What factors predict anxiety and depression during pregnancy and after birth? Review, 2010 Can neurosteroids help with anxiety and brain disorders? Case-control study, 2010 Do lesbian and bisexual women have different reproductive health than heterosexual women? Review, 2003 Do GABA receptors and progesterone affect PMDD? Ask AI about this page Copy prompt ChatGPT ↗ Claude ↗ Perplexity ↗ Google AI Mode ↗ Grok ↗