--- title: Among women with bipolar I disorder, who is more likely to also have PMDD? description: About one-third (36.5%) of women with bipolar I disorder have PMDD. Those at higher risk have seasonal mood patterns, a history of suicide attempts, and a fam url: https://niyora.com/research/papers/profile-and-predictors-of-premenstrual-dysphoric-disorder-in-women-with-bipolar-2026/ --- - [Niyora](https://niyora.com/) - [Research](https://niyora.com/research/) - [Library](https://niyora.com/research/library/) - Among women with bipolar I disorder, who is more likely to also have PMDD? Survey study, 2026 # Among women with bipolar I disorder, who is more likely to also have PMDD? About one-third (36.5%) of women with bipolar I disorder have PMDD. Those at higher risk have seasonal mood patterns, a history of suicide attempts, and a family history of mental illness. Early or limited evidence 85 premenopausal women aged 18-45 with bipolar I disorder in clinical remission, India ## What they did Cross-sectional study of 85 premenopausal women aged 18-45 with bipolar I disorder who were not currently in an active mood episode. They completed multiple standardized assessments for bipolar disorder and PMDD. ## What they found 36.5% met the threshold for PMDD. Average age was 30.68 years. Both bipolar disorder and PMDD typically started around age 21-22 years. Women with both conditions had earlier bipolar onset, depressive episodes when bipolar disorder started, and more atypical bipolar features. Factors associated with increased likelihood of PMDD included global seasonality score, lifetime suicide attempt, and family history of psychiatric illness. History of pregnancy was associated with lower likelihood of PMDD. ## What it means for you Women with bipolar I disorder face high risk of also having PMDD (about 1 in 3). Seasonal mood patterns and past suicide attempts are warning signs that a woman might have both conditions. This helps doctors know who should be screened. The main limit is that this is one study in one location, so results may not apply to women with bipolar disorder in other countries. 85 women with bipolar I disorder 36.5% met threshold for PMDD 30.68 average age of participants ## About the study Original title Profile and predictors of premenstrual dysphoric disorder in women with bipolar I disorder: An exploratory study from India Authors Tina Khwairakpam, Pratap Sharan, Raman Deep et al. Journal Industrial Psychiatry Journal Year 2026 Study design Survey study Participants 85 Open access Yes Read the paper [doi.org/10.4103/ipj.ipj_467_25](https://doi.org/10.4103/ipj.ipj_467_25) ## Topics [Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Premenstrual dysphoric disorder (PMDD)](https://niyora.com/research/topics/condition-pmdd/)[Low mood and depression](https://niyora.com/research/topics/symptom-depression-mood/)[Anxiety and tension](https://niyora.com/research/topics/symptom-anxiety/)[Suicidality](https://niyora.com/research/topics/symptom-suicidality/)[Anxiolytics and other psychotropics](https://niyora.com/research/topics/treatment-anxiolytics/)[Bipolar disorder](https://niyora.com/research/topics/comorbidity-bipolar/) Research tells you what helps on average. Niyora helps on the day it hits. Calm down, see it another way, and decide what to say, with a PMS and PMDD app built by a doctor. ## Related studies Case report, 2013 Can severe mood changes around a period be an early sign of bipolar disorder? Review, 2003 How do menstrual cycle hormones affect the brain and cause mood disorders like PMDD? Study, 2026 Do anxiety and depression get worse before your period if you already have a mental health condition? Cohort study, 2004 Do women with bipolar disorder on mood-stabilizing medication experience premenstrual symptom worsening? Review, 1999 How should severe premenstrual dysphoric disorder be diagnosed and treated? Randomised trial, 1994 Does alprazolam help women with late luteal phase dysphoric disorder? Ask AI about this page Copy prompt ChatGPT ↗ Claude ↗ Perplexity ↗ Google AI Mode ↗ Grok ↗