---
title: How does the traditional Chinese medicine Chaihu Shugan Powder work to treat PMS?
description: This review identifies that the formula may work through 17 signaling pathways and 75 molecular targets to reduce PMS symptoms. However, the mechanism has onl
url: https://niyora.com/research/papers/research-progress-of-traditional-chinese-medicine-compound-chaihu-shugan-powder-2024/
---

- [Niyora](https://niyora.com/)
- [Research](https://niyora.com/research/)
- [Library](https://niyora.com/research/library/)
- How does the traditional Chinese medicine Chaihu Shugan Powder work to treat PMS?

Review, 2024

# How does the traditional Chinese medicine Chaihu Shugan Powder work to treat PMS?

This review identifies that the formula may work through 17 signaling pathways and 75 molecular targets to reduce PMS symptoms. However, the mechanism has only been studied theoretically and no clinical trials have tested it yet.

 Early or limited evidence

Literature review of a traditional Chinese medicine formula (no new participants)

## What they did

Literature review analyzing the traditional Chinese medicine formula Chaihu Shugan Powder using network pharmacology. Researchers reviewed literature on ingredients and mechanisms, then used computer analysis to identify molecular targets and pathways.

## What they found

The formula contains 7 herbal ingredients with multiple active compounds. Network pharmacology identified 75 common molecular targets relevant to PMS treatment, concentrated in 17 signaling pathways. The formula has been traditionally used for liver detoxification and depression relief and is one of the most widely used formulas for treating PMS.

## What it means for you

The formula may work through multiple molecular pathways. However, this was only a literature and computer analysis. No laboratory, animal, or human experiments were conducted. Clinical trials are needed to know if it actually works and which ingredients are responsible.

7

herbal ingredients in the formula

75

molecular targets identified

17

signaling pathways identified

## About the study

Original title Research progress of traditional Chinese medicine compound "Chaihu Shugan Powder" in the treatment of premenstrual syndrome Authors Chu Z, Gao M, Wang J et al. Journal Medicine Year 2024 Study design Review What was tested Chaihu Shugan Powder (traditional Chinese medicine formula) - theoretical analysis only Open access Yes Read the paper [doi.org/10.1097/md.0000000000038351](https://doi.org/10.1097/md.0000000000038351)

## Topics

[Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Other herbal medicine](https://niyora.com/research/topics/treatment-herbal-other/)

Research tells you what helps on average. Niyora helps on the day it hits.

Calm down, see it another way, and decide what to say, with a PMS and PMDD app built by a doctor.

## Related studies

Systematic review, 2026

Which traditional Chinese medicine treatments work best for PMS?

Randomised trial, 2025

Do essential oils reduce PMS symptoms?

Randomised trial, 2025

Which is more effective for PMS - Vitagnus, soy, or both together?

Randomised trial, 2025

Does the PMSoff supplement help PMS and PMDD symptoms?

Randomised trial, 2024

Is Jiawei Xiaoyao pill effective and safe for treating premenstrual syndrome?

Randomised trial, 2024

Is Ganyushu Granule effective and safe for premenstrual syndrome?

Ask AI about this page

Copy prompt

ChatGPT

↗

Claude

↗

Perplexity

↗

Google AI Mode

↗

Grok

↗