---
title: Does calcium and vitamin D deficiency cause PMS? | Niyora
description: Evidence suggests that calcium and vitamin D deficiency may cause PMS symptoms during the luteal phase. Calcium and vitamin D supplements may help treat PMS.
url: https://niyora.com/research/papers/role-of-calcium-metabolism-in-premenstrual-syndrome-2008/
---

- [Niyora](https://niyora.com/)
- [Research](https://niyora.com/research/)
- [Library](https://niyora.com/research/library/)
- Does calcium and vitamin D deficiency cause PMS?

Study, 2008

# Does calcium and vitamin D deficiency cause PMS?

Evidence suggests that calcium and vitamin D deficiency may cause PMS symptoms during the luteal phase. Calcium and vitamin D supplements may help treat PMS.

 Early or limited evidence

Review of evidence about PMS in women.

## What they did

This article reviewed scientific evidence about how calcium and vitamin D relate to PMS.

## What they found

During the menstrual cycle, hormonal changes affect how your body absorbs calcium from food and produces vitamin D. Low calcium and vitamin D levels appear to be linked to PMS symptoms. The article suggests that calcium and vitamin D supplements might help many women with PMS.

## What it means for you

If calcium and vitamin D deficiency is truly a cause of PMS, then supplementing these nutrients could be a simple solution for many women. However, this is a review of existing evidence, not a report of new research testing this idea.

2

key nutrients

## About the study

Original title Role of calcium metabolism in premenstrual syndrome Authors Bocchieri E, Thys-Jacobs S Journal Expert review of endocrinology & metabolism Year 2008 Study design Study What was tested Calcium and vitamin D supplementation (proposed). Read the paper [doi.org/10.1586/17446651.3.5.645](https://doi.org/10.1586/17446651.3.5.645)

## Topics

[Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Premenstrual dysphoric disorder (PMDD)](https://niyora.com/research/topics/condition-pmdd/)[Menstrual cycle and mood](https://niyora.com/research/topics/condition-cycle-mood/)[Low mood and depression](https://niyora.com/research/topics/symptom-depression-mood/)[Calcium](https://niyora.com/research/topics/treatment-calcium/)[Vitamin D](https://niyora.com/research/topics/treatment-vitamin-d/)[Thyroid disorders](https://niyora.com/research/topics/comorbidity-thyroid/)

Research tells you what helps on average. Niyora helps on the day it hits.

Calm down, see it another way, and decide what to say, with a PMS and PMDD app built by a doctor.

## Related studies

Cohort study, 2007

Is there something different about calcium and vitamin D levels in women with PMDD?

Review, 2011

What are PMS and PMDD, and how common are they?

Study, 2026

What are premenstrual syndrome and premenstrual dysphoric disorder?

Review, 2016

How common are PMS and PMDD, and what are the best treatments?

Review, 2003

What treatments work best for PMS and PMDD?

Review, 2000

Can calcium and vitamin D help with PMS symptoms?

Ask AI about this page

Copy prompt

ChatGPT

↗

Claude

↗

Perplexity

↗

Google AI Mode

↗

Grok

↗