---
title: Is PMDD related to other mood disorders like depression? | Niyora
description: PMDD shares many symptoms with depression and other mood disorders and is classified with them in diagnostic manuals. However, important differences suggest P
url: https://niyora.com/research/papers/the-association-between-premenstrual-dysphoric-disorder-and-other-mood-disorders-1997/
---

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- Is PMDD related to other mood disorders like depression?

Interview study, 1997

# Is PMDD related to other mood disorders like depression?

PMDD shares many symptoms with depression and other mood disorders and is classified with them in diagnostic manuals. However, important differences suggest PMDD is distinct, though its exact relationship remains unclear.

 Early or limited evidence

Literature review (no specific study population)

## What they did

Examined published research on PMDD's epidemiology, symptoms, family history, biology, and treatment to compare with features of other mood disorders.

## What they found

Women with PMDD and patients with other mood disorders experience overlapping symptoms. Past mood disorder episodes and family history are common in PMDD. Some biological markers and antidepressants work for both conditions. However, certain biological features, cognitive patterns, and treatment responses differentiate PMDD from other mood disorders.

## What it means for you

PMDD shares features with depression and other mood disorders but is also distinct from them. The classification of PMDD with mood disorders in diagnostic manuals has some support but does not mean PMDD is simply depression. More research is needed to clarify the relationships.

## About the study

Original title The association between premenstrual dysphoric disorder and other mood disorders Authors Yonkers KA Journal The Journal of clinical psychiatry Year 1997 Study design Interview study What was tested Not applicable - literature review Read the paper [https://pubmed.ncbi.nlm.nih.gov/9427873/](https://pubmed.ncbi.nlm.nih.gov/9427873/)

## Topics

[Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Premenstrual dysphoric disorder (PMDD)](https://niyora.com/research/topics/condition-pmdd/)[Menstrual cycle and mood](https://niyora.com/research/topics/condition-cycle-mood/)[Low mood and depression](https://niyora.com/research/topics/symptom-depression-mood/)[SSRIs and antidepressants](https://niyora.com/research/topics/treatment-ssri/)[Major depressive disorder](https://niyora.com/research/topics/comorbidity-major-depression/)

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## Related studies

Randomised trial, 2000

Does sertraline improve how women with PMDD feel and function?

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Do anxiety and depression get worse before your period if you already have a mental health condition?

Study, 2026

What treatments work for PMDD?

Cohort study, 2022

What are PMS and PMDD and how should they be diagnosed and treated?

Cohort study, 2012

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Review, 2012

Is depression linked to hormonal changes during the menstrual cycle, pregnancy, and menopause?

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