---
title: Are zinc and copper levels linked to PMS in teenage girls? | Niyora
description: The study found that girls with both irritable bowel syndrome and period pain had lower dietary zinc intake, but did not find a clear link between minerals an
url: https://niyora.com/research/papers/the-association-of-trace-elements-with-premenstrual-syndrome-dysmenorrhea-and-2019/
---

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- Are zinc and copper levels linked to PMS in teenage girls?

Case-control study, 2019

# Are zinc and copper levels linked to PMS in teenage girls?

The study found that girls with both irritable bowel syndrome and period pain had lower dietary zinc intake, but did not find a clear link between minerals and PMS alone.

 Early or limited evidence

448 teenage girls divided by period and digestive symptoms

## What they did

Researchers measured zinc and copper in blood and diet of 448 teenage girls. Girls were divided into four groups: PMS only (67), painful periods only (161), both PMS and painful periods (146), and no symptoms (74). Blood tests and food records measured mineral levels.

## What they found

Dietary zinc intake was significantly lower in girls with irritable bowel syndrome (6.7 ± 2.8 mg/day) versus those without it (7.9 ± 3.1 mg/day). Irritable bowel syndrome was more common in girls with painful periods (19.9%) and those with both conditions (17.4%) than PMS alone (13.6%) or normal (8.1%).

## What it means for you

Lower zinc intake may matter for girls with both period pain and digestive problems. Results are unclear about whether zinc helps PMS specifically since the study cannot prove causation from this observational design.

6.7 ± 2.8 mg/day

zinc in girls with IBS

7.9 ± 3.1 mg/day

zinc in girls without IBS

19.9%

IBS in girls with painful periods

## About the study

Original title The association of trace elements with premenstrual syndrome, dysmenorrhea and irritable bowel syndrome in adolescents Authors Bahrami A, Gonoodi K, Khayyatzadeh SS et al. Journal European journal of obstetrics, gynecology, and reproductive biology Year 2019 Study design Case-control study Participants 161 What was tested No intervention - observational study of mineral intake Read the paper [doi.org/10.1016/j.ejogrb.2018.12.017](https://doi.org/10.1016/j.ejogrb.2018.12.017)

## Topics

[Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Dysmenorrhea and period pain](https://niyora.com/research/topics/condition-dysmenorrhea/)[Irritability and anger](https://niyora.com/research/topics/symptom-irritability-anger/)[Diet and nutrition](https://niyora.com/research/topics/treatment-diet/)[Zinc and iron](https://niyora.com/research/topics/treatment-zinc-iron/)[IBS and gut symptoms](https://niyora.com/research/topics/comorbidity-ibs-gi/)[Adolescents and young people](https://niyora.com/research/topics/life-area-adolescents/)

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