---
title: Do girls with PMS have different estrogen levels than those without?
description: Girls with PMS had higher estrogen levels than those without. Girls with severe PMS had the highest levels. This is a one-time measurement, so we cannot tell
url: https://niyora.com/research/papers/the-effect-of-estrogen-hormone-on-premenstrual-syndrome-pms-occurrences-in-2021/
---

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- Do girls with PMS have different estrogen levels than those without?

Survey study, 2021

# Do girls with PMS have different estrogen levels than those without?

Girls with PMS had higher estrogen levels than those without. Girls with severe PMS had the highest levels. This is a one-time measurement, so we cannot tell if high estrogen causes PMS.

 Early or limited evidence

50 teenage girls (25 with PMS, 25 without) at Pesantren Darul Arqam, Makassar

## What they did

Researchers compared 25 teenage girls with PMS to 25 without PMS. Girls with PMS kept daily symptom diaries and provided blood samples. Estrogen was measured using a lab test called ELISA. The study lasted 3 months.

## What they found

The mean estrogen level in girls with PMS was 148.32 pg/ml, compared to 98.00 pg/ml in girls without PMS. Girls with mild PMS had 130.73 pg/ml and those with severe PMS had 162.14 pg/ml. The difference was significant.

## What it means for you

Higher estrogen is linked to PMS in teenage girls, and severe PMS is linked to even higher estrogen. The study measured estrogen only once, so we don't know if this changes through the cycle or if high estrogen actually causes PMS.

148.32

mean estrogen level in girls with PMS (pg/ml)

98.00

mean estrogen level in girls without PMS (pg/ml)

162.14

mean estrogen level in girls with severe PMS (pg/ml)

## About the study

Original title The effect of estrogen hormone on premenstrual syndrome (PMS) occurrences in teenage girls at Pesantren Darul Arqam Makassar Authors Noviyanti NI, Gusriani, Ruqaiyah et al. Journal Gaceta sanitaria Year 2021 Study design Survey study What was tested None; this was an observational measurement study. Open access Yes Read the paper [doi.org/10.1016/j.gaceta.2021.10.103](https://doi.org/10.1016/j.gaceta.2021.10.103)

## Topics

[Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Anxiety and tension](https://niyora.com/research/topics/symptom-anxiety/)[Adolescents and young people](https://niyora.com/research/topics/life-area-adolescents/)

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