--- title: Do women with polycystic ovary syndrome have more severe premenstrual symptoms and mental health problems? description: Women with PCOS had significantly more water retention before their period and higher weight, but the study found no significant differences in mental health url: https://niyora.com/research/papers/the-effect-of-polycystic-ovary-syndrome-on-mental-health-and-physical-and-2025/ --- - [Niyora](https://niyora.com/) - [Research](https://niyora.com/research/) - [Library](https://niyora.com/research/library/) - Do women with polycystic ovary syndrome have more severe premenstrual symptoms and mental health problems? Case-control study, 2025 # Do women with polycystic ovary syndrome have more severe premenstrual symptoms and mental health problems? Women with PCOS had significantly more water retention before their period and higher weight, but the study found no significant differences in mental health scores compared to women without PCOS. Moderate study design 340 women aged 15-20 years (170 with PCOS, 170 without) in Shiraz, Iran. ## What they did Case-control study in 2017 comparing 170 women with PCOS to 170 healthy women aged 15-20 years. Participants in Shiraz, Iran completed questionnaires about demographics, PCOS diagnosis, general health, and premenstrual symptoms. Data were analyzed using statistical tests. ## What they found The PCOS group had significantly higher average weight and BMI compared to the control group (P less than 0.001). Premenstrual edema was significantly more common in the PCOS group (P equals 0.003). There were no significant differences in mental health scores, height, or age at first menstruation. ## What it means for you PCOS may be linked to physical premenstrual symptoms like water retention and weight gain, but this study found no mental health differences. Main limitations include being conducted in one city, including only young women aged 15-20, and using 2017 data. Physical problems may affect mental health over time. 340 Total number of women studied P<0.001 Statistical significance of weight and BMI difference P=0.003 Statistical significance of premenstrual edema difference ## About the study Original title The effect of polycystic ovary syndrome on mental health and physical and psychological symptoms before menstruation: A case-control study Authors Solmaz Golestan, Bahar Morshed-Behbahani, Maryam Keshavarz Journal Payesh (Health Monitor) Journal Year 2025 Study design Case-control study Participants 340 What was tested None; this was an observational comparison between women with and without PCOS. Open access Yes Read the paper [doi.org/10.61882/payesh.24.5.697](https://doi.org/10.61882/payesh.24.5.697) ## Topics [Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Polycystic ovary syndrome (PCOS)](https://niyora.com/research/topics/comorbidity-pcos/) Research tells you what helps on average. Niyora helps on the day it hits. Calm down, see it another way, and decide what to say, with a PMS and PMDD app built by a doctor. ## Related studies Cohort study, 2025 Does having PCOS raise the risk of premenstrual disorders like PMS or PMDD? Systematic review, 2010 Does acupuncture treat premenstrual syndrome? Cohort study, 2026 Does having worse premenstrual symptoms mean you are more likely to get pregnant? Cohort study, 2026 Do early-life exposures like antibiotics or breastfeeding affect PMS risk? Randomised trial, 2026 Does vitamin D help with PMS symptoms? Systematic review, 2025 Does seed cycling reduce PMS symptoms? Ask AI about this page Copy prompt ChatGPT ↗ Claude ↗ Perplexity ↗ Google AI Mode ↗ Grok ↗