--- title: Do adolescents with PMS have different heart rate patterns than those without PMS? description: No clear difference was found. Heart rate measurements during different parts of the menstrual cycle were similar in adolescents with PMS and those without PM url: https://niyora.com/research/papers/the-evaluation-of-autonomic-dysfunction-in-adolescent-patients-with-premenstrual-2024/ --- - [Niyora](https://niyora.com/) - [Research](https://niyora.com/research/) - [Library](https://niyora.com/research/library/) - Do adolescents with PMS have different heart rate patterns than those without PMS? Case-control study, 2024 # Do adolescents with PMS have different heart rate patterns than those without PMS? No clear difference was found. Heart rate measurements during different parts of the menstrual cycle were similar in adolescents with PMS and those without PMS. Moderate study design 48 adolescents aged 12 to 18 years, with 29 diagnosed with PMS and 19 without PMS. ## What they did Measured heart rate in 48 adolescents (29 with PMS, 19 without) using heart rate recordings during both the first and second halves of the menstrual cycle. ## What they found Heart rate measurements including heart rate, time intervals between beats, and rhythm patterns did not differ between the PMS group and the control group, or between the first half and second half of the menstrual cycle. ## What it means for you In adolescents, PMS does not appear to affect how the nervous system controls the heart. This might be because adolescents' bodies are still developing or because they have milder PMS symptoms. The main limitation is the small sample size and that only adolescents were studied, so these results may not apply to adult women. 48 total adolescents studied 29 with PMS 19 without PMS ## About the study Original title The Evaluation of Autonomic Dysfunction in Adolescent Patients with Premenstrual Syndrome Authors Özlem Akbulut, İlker Ertuğrul, Melis Pehlivantürk Kızılkan et al. Journal Archives of Obstetrics and Gynaecology Year 2024 Study design Case-control study Participants 48 What was tested None; observational study Open access Yes Read the paper [doi.org/10.33696/gynaecology.5.067](https://doi.org/10.33696/gynaecology.5.067) Original abstract Introduction: The relationship between premenstrual syndrome (PMS) and autonomic nervous system (ANS) is complex, with limited data on PMS-related stress further inducing disturbances in the ANS balance. We aimed to investigate the ANS functions through heart rate changes in adolescents with and without PMS. Method: Participants aged 12-18 years were evaluated for the presence of PMS with the premenstrual syndrome scale and seperated into PMS and control groups. All participants were evaluated by 12-lead surface electrocardiography (ECG) and 24-hour rhythm Holter recordings during the follicular and luteal phases of the menstrual cycle. Results: A total of 48 participants (29 PMS, 19 control) were included in our study. The mean age was 15.37 ± 1.42 years in the PMS group and 14.66 ± 1.36 years in the control group. ECG (ventricular rate, PR interval, QRS duration, QT and QTc) and holter (SDNN-ms, SDNNi, RMS_SD, Triangular index) data did not differ in both groups and between phases. Conclusions: Our results showed that autonomic activity in adolescents with PMS does not vary from that of the control group or according to menstrual cycle phases. This might be attributed to the potential correlation between the augmentation of autonomic activity response and both age and the severity of the illness. Reproduced under CC-BY. ## Topics [Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Adolescents and young people](https://niyora.com/research/topics/life-area-adolescents/) Research tells you what helps on average. Niyora helps on the day it hits. Calm down, see it another way, and decide what to say, with a PMS and PMDD app built by a doctor. ## Related studies Randomised trial, 2026 Does aerobic or resistance exercise reduce anxiety in women with PMS? Cohort study, 2025 How common is PMS in Chinese teenage girls, and what factors are linked to it? Systematic review, 2025 Does alcohol use affect menstrual health in teenage girls? Systematic review, 2025 Does teaching adolescent girls about their menstrual cycle and health help reduce period pain and PMS? Randomised trial, 2024 Does curcumin-piperine combination improve antioxidant activity in women with PMS and period pain? Systematic review, 2024 How common is premenstrual syndrome in Africa, and what factors increase the risk? Ask AI about this page Copy prompt ChatGPT ↗ Claude ↗ Perplexity ↗ Google AI Mode ↗ Grok ↗