--- title: Are PMS or PMDD linked to different features of bipolar disorder in women? description: Yes. Women with bipolar disorder and PMS or PMDD became ill at younger ages, had worse depression symptoms with more anxiety and thinking problems, and were m url: https://niyora.com/research/papers/the-impact-of-comorbid-premenstrual-syndrome-or-premenstrual-dysphoric-disorder-2024/ --- - [Niyora](https://niyora.com/) - [Research](https://niyora.com/research/) - [Library](https://niyora.com/research/library/) - Are PMS or PMDD linked to different features of bipolar disorder in women? Survey study, 2024 # Are PMS or PMDD linked to different features of bipolar disorder in women? Yes. Women with bipolar disorder and PMS or PMDD became ill at younger ages, had worse depression symptoms with more anxiety and thinking problems, and were more likely to have OCD or family history of mental illness. This is observational, so we cannot prove cause and effect. Early or limited evidence 262 Chinese women with bipolar disorder ## What they did Researchers studied 262 Chinese women with bipolar disorder. They used a screening tool to identify PMS and PMDD, and measured depression and mania symptoms using established rating scales. ## What they found About 57.6% of women with bipolar disorder had PMS and 20.6% had PMDD. Women with both conditions started becoming ill younger, had higher depression scores (especially for anxiety and thinking problems), were more likely to have obsessive-compulsive disorder, and those with PMDD were more likely to have family members with mental illness. ## What it means for you Bipolar disorder combined with PMS or PMDD might be a distinct form of the illness with earlier onset and worse symptoms. The main limit is that this is observational, so we cannot tell whether PMS or PMDD causes these features or simply occurs alongside them. 57.6% women with bipolar disorder who had PMS 20.6% women with bipolar disorder who had PMDD 262 women studied ## About the study Original title The impact of comorbid premenstrual syndrome or premenstrual dysphoric disorder on the clinical characteristics of bipolar disorder among Han Chinese women Authors Liang X, Yang T, Liao Y et al. Journal Archives of women's mental health Year 2024 Study design Survey study Participants 262 What was tested None Read the paper [doi.org/10.1007/s00737-023-01380-7](https://doi.org/10.1007/s00737-023-01380-7) ## Topics [Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Premenstrual dysphoric disorder (PMDD)](https://niyora.com/research/topics/condition-pmdd/)[Low mood and depression](https://niyora.com/research/topics/symptom-depression-mood/)[Anxiety and tension](https://niyora.com/research/topics/symptom-anxiety/)[Cognition, concentration and memory](https://niyora.com/research/topics/symptom-cognition/)[Bipolar disorder](https://niyora.com/research/topics/comorbidity-bipolar/)[Anxiety disorders and OCD](https://niyora.com/research/topics/comorbidity-anxiety-disorders/) Research tells you what helps on average. Niyora helps on the day it hits. Calm down, see it another way, and decide what to say, with a PMS and PMDD app built by a doctor. ## Related studies Study, 2026 Do anxiety and depression get worse before your period if you already have a mental health condition? Randomised trial, 2002 Is fluoxetine or cognitive-behavioral therapy more effective for PMDD? Survey study, 2026 Are PMDD, anxiety, and internet use linked to cognitive problems in women? Study, 2025 Could taking a combination of vitamins and minerals help with PMS and PMDD symptoms? Randomised trial, 2020 How should premenstrual syndrome be diagnosed and treated? Non-randomised trial, 2001 Do people with PMDD have different breathing patterns? Ask AI about this page Copy prompt ChatGPT ↗ Claude ↗ Perplexity ↗ Google AI Mode ↗ Grok ↗