---
title: What herbs and dietary supplements have evidence for treating premenstrual syndrome?
description: A review of research found that calcium, vitamin B6, and chasteberry have the strongest evidence from clinical trials for treating premenstrual syndrome.
url: https://niyora.com/research/papers/the-use-of-herbs-and-dietary-supplements-in-gynecology-an-evidence-based-review-2006/
---

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- What herbs and dietary supplements have evidence for treating premenstrual syndrome?

Randomised trial, 2006

# What herbs and dietary supplements have evidence for treating premenstrual syndrome?

A review of research found that calcium, vitamin B6, and chasteberry have the strongest evidence from clinical trials for treating premenstrual syndrome.

 Strong study design

Multiple randomized controlled trials reviewed

## What they did

Evidence-based review of published studies examining herbs and dietary supplements for gynecologic conditions including menopause, premenstrual syndrome, dysmenorrhea, cyclic mastalgia, and infertility. The review evaluated the quality of evidence from randomized controlled trials.

## What they found

For premenstrual syndrome: calcium, vitamin B6, and chasteberry were identified as having higher levels of support from randomized controlled trial evidence. For other gynecologic conditions: black cohosh for menopause, vitamins B1 and E for dysmenorrhea, and chasteberry for cyclic mastalgia had evidence. For infertility, too few trials existed, but chasteberry, antioxidants, and Fertility Blend had some preliminary support.

## What it means for you

When prescription medications are not working well or cause side effects, some herbs and supplements have been studied in clinical trials for PMS and other gynecologic conditions. Calcium, B6, and chasteberry have the most evidence for PMS. However, most alternative treatments need more research before strong recommendations can be made.

3

Therapies with evidence for PMS

5

Gynecologic conditions reviewed

2006

Publication year

## About the study

Original title The use of herbs and dietary supplements in gynecology: an evidence-based review Authors Dennehy CE Journal Journal of midwifery & women's health Year 2006 Study design Randomised trial What was tested Evidence review of herbs and supplements for gynecologic conditions Read the paper [doi.org/10.1016/j.jmwh.2006.01.004](https://doi.org/10.1016/j.jmwh.2006.01.004)

## Topics

[Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Dysmenorrhea and period pain](https://niyora.com/research/topics/condition-dysmenorrhea/)[Bloating, breast tenderness and physical symptoms](https://niyora.com/research/topics/symptom-physical-symptoms/)[Diet and nutrition](https://niyora.com/research/topics/treatment-diet/)[Calcium](https://niyora.com/research/topics/treatment-calcium/)[Vitex agnus-castus (chasteberry)](https://niyora.com/research/topics/treatment-vitex/)[Other herbal medicine](https://niyora.com/research/topics/treatment-herbal-other/)[Perimenopause and menopause](https://niyora.com/research/topics/comorbidity-perimenopause/)[Stigma, attitudes and culture](https://niyora.com/research/topics/life-area-stigma-culture/)

Research tells you what helps on average. Niyora helps on the day it hits.

Calm down, see it another way, and decide what to say, with a PMS and PMDD app built by a doctor.

## Related studies

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Survey study, 2023

Can diet help reduce PMS symptoms?

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Review, 2021

Do herbal products help with PMS?

Survey study, 2012

What non-hormonal medications and therapies help severe PMS and PMDD?

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