---
title: Does a traditional Japanese herbal medicine help PMS symptoms?
description: In a small test, Keishi-bukuryo-gan reduced PMS symptoms in all 4 women who took it, with 2 showing major improvement and 2 showing some improvement.
url: https://niyora.com/research/papers/therapeutic-effect-of-keishi-bukuryo-gan-on-premenstrual-syndrome-newly-1994/
---

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- Does a traditional Japanese herbal medicine help PMS symptoms?

Study, 1994

# Does a traditional Japanese herbal medicine help PMS symptoms?

In a small test, Keishi-bukuryo-gan reduced PMS symptoms in all 4 women who took it, with 2 showing major improvement and 2 showing some improvement.

 Early or limited evidence

4 women with PMS in Japan

## What they did

Four women with PMS were given Keishi-bukuryo-gan extract (TJ-25). Before and after treatment, their PMS was scored on a system rating emotional, neurological, breast, fluid-related, stomach, and skin symptoms, for a total score out of 100.

## What they found

Of 4 women treated, 2 had major improvement (symptom score dropped to 30% or less of their starting score), and 2 had improvement (score dropped to 31 to 60% of their starting score). No side effects were reported.

## What it means for you

This herbal medicine might help PMS symptoms. However, this is a very small study with only 4 women and no comparison group, so we cannot be sure the medicine caused the improvement.

4

women treated

30%

or less score reduction for major improvement

100

total points on symptom scale

## About the study

Original title Therapeutic Effect of "Keishi-bukuryo-gan" on Premenstrual Syndrome. Newly developed "PMS Scores(Jikei)" and their application Authors Kazunori Ochiai, Kazunori Matsumoto, Yoshiteru Terashima Journal 日本東洋醫學雜誌 Year 1994 Study design Study What was tested Keishi-bukuryo-gan extract (TJ-25), a traditional Japanese herbal medicine Open access Yes Read the paper [doi.org/10.3937/kampomed.45.365](https://doi.org/10.3937/kampomed.45.365)

## Topics

[Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)

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