---
title: Does Vitex agnus castus help cyclical breast pain? | Niyora
description: Yes. The extract reduced breast pain faster than placebo and was well tolerated.
url: https://niyora.com/research/papers/treatment-of-cyclical-mastodynia-using-an-extract-of-vitex-agnus-castus-results-1998/
---

- [Niyora](https://niyora.com/)
- [Research](https://niyora.com/research/)
- [Library](https://niyora.com/research/library/)
- Does Vitex agnus castus help cyclical breast pain?

Randomised trial, 1998

# Does Vitex agnus castus help cyclical breast pain?

Yes. The extract reduced breast pain faster than placebo and was well tolerated.

 Moderate study design

97 women with breast pain for at least 5 days of their menstrual cycle

## What they did

In a double-blind, placebo-controlled study, 97 women with cyclical breast pain were randomly assigned to Vitex agnus castus extract or placebo. Women took either the extract (1.8 ml daily in two 30-drop doses) or placebo pills daily for 3 consecutive menstrual cycles. Pain was measured on a visual pain scale.

## What they found

Breast pain intensity decreased more quickly in the Vitex group than the placebo group. The extract had satisfactory tolerability with few side effects reported.

## What it means for you

Vitex may help reduce cyclical breast pain faster than placebo. The main limits are that the abstract does not specify how much pain reduction occurred or give statistical significance, and the sample size is relatively small.

97

Women in the study

3

Menstrual cycles of treatment

1.8 ml

Daily dose of Vitex

## About the study

Original title [Treatment of cyclical mastodynia using an extract of Vitex agnus castus: results of a double-blind comparison with a placebo] Authors Halaska M, Raus K, Bĕles P et al. Journal Ceska gynekologie Year 1998 Study design Randomised trial Participants 49 What was tested Vitex agnus castus 1.8 ml daily Read the paper [https://pubmed.ncbi.nlm.nih.gov/9818496/](https://pubmed.ncbi.nlm.nih.gov/9818496/)

## Topics

[Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Bloating, breast tenderness and physical symptoms](https://niyora.com/research/topics/symptom-physical-symptoms/)[Pain and headache](https://niyora.com/research/topics/symptom-pain/)[Vitex agnus-castus (chasteberry)](https://niyora.com/research/topics/treatment-vitex/)

Research tells you what helps on average. Niyora helps on the day it hits.

Calm down, see it another way, and decide what to say, with a PMS and PMDD app built by a doctor.

## Related studies

Systematic review, 2020

Does Vitex agnus-castus help cyclic breast pain?

Cohort study, 2024

Does Vitex supplement improve menstrual cycle problems and quality of life?

Randomised trial, 2019

Does chasteberry (Vitex agnus-castus) help premenstrual breast pain and related symptoms?

Randomised trial, 2026

Do seed cycling capsules with chasteberry reduce PMS symptoms over two months?

Survey study, 2025

Can a plant-based supplement reduce PMS symptoms?

Randomised trial, 2017

Can chasteberry (Vitex agnus castus) help premenstrual breast pain and PMS?

Ask AI about this page

Copy prompt

ChatGPT

↗

Claude

↗

Perplexity

↗

Google AI Mode

↗

Grok

↗