---
title: What treatments work for premenstrual disorders? | Niyora
description: Several treatments work. Three SSRIs are FDA-approved for PMDD. Exercise, diet changes, and therapy also help some women, but no single treatment works for ev
url: https://niyora.com/research/papers/treatment-of-premenstrual-disorders-2006/
---

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- What treatments work for premenstrual disorders?

Review, 2006

# What treatments work for premenstrual disorders?

Several treatments work. Three SSRIs are FDA-approved for PMDD. Exercise, diet changes, and therapy also help some women, but no single treatment works for everyone.

 Moderate study design

Women with premenstrual disorders and PMDD (review article)

## What they did

Review of treatment approaches for premenstrual disorders, including non-drug options and various medications.

## What they found

Non-drug treatments that help include aerobic exercise, dietary changes and supplements, and cognitive-behavioral therapy. Three SSRIs have FDA approval for PMDD. Spironolactone and birth control pills are used off-label. A birth control pill containing drospirenone is effective for reducing premenstrual symptoms. A newer drospirenone pill given for 24 days out of a 28-day cycle is effective for PMDD.

## What it means for you

If you have premenstrual symptoms, many treatment options exist. SSRIs are proven to work for PMDD. Exercise and diet changes help too. If you're considering birth control pills, drospirenone-containing pills have good evidence. This is a review of research from 2006 and earlier.

3

SSRIs with FDA approval for PMDD

24 days

Duration pill is taken per 28-day cycle

## About the study

Original title Treatment of premenstrual disorders Authors Kroll R, Rapkin AJ Journal The Journal of reproductive medicine Year 2006 Study design Review Read the paper [https://pubmed.ncbi.nlm.nih.gov/16734319/](https://pubmed.ncbi.nlm.nih.gov/16734319/)

## Topics

[Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Premenstrual dysphoric disorder (PMDD)](https://niyora.com/research/topics/condition-pmdd/)[Cognition, concentration and memory](https://niyora.com/research/topics/symptom-cognition/)[SSRIs and antidepressants](https://niyora.com/research/topics/treatment-ssri/)[Oral contraceptives and drospirenone](https://niyora.com/research/topics/treatment-hormonal-contraceptives/)[GnRH agonists and ovarian suppression](https://niyora.com/research/topics/treatment-gnrh/)[Cognitive behavioral therapy](https://niyora.com/research/topics/treatment-cbt/)[Exercise and yoga](https://niyora.com/research/topics/treatment-exercise/)[Anxiolytics and other psychotropics](https://niyora.com/research/topics/treatment-anxiolytics/)[Diuretics and other drugs](https://niyora.com/research/topics/treatment-diuretics-other-drugs/)

Research tells you what helps on average. Niyora helps on the day it hits.

Calm down, see it another way, and decide what to say, with a PMS and PMDD app built by a doctor.

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