---
title: Does vitamin B6 help PMS? | Niyora
description: The evidence is weak. A review of 12 controlled trials found some positive effects, but the trials were too small to be convincing about whether vitamin B6 tr
url: https://niyora.com/research/papers/vitamin-b6-in-the-treatment-of-the-premenstrual-syndrome-a-review-1990/
---

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- Does vitamin B6 help PMS?

Randomised trial, 1990

# Does vitamin B6 help PMS?

The evidence is weak. A review of 12 controlled trials found some positive effects, but the trials were too small to be convincing about whether vitamin B6 truly helps PMS.

 Early or limited evidence

Review of 12 controlled trials (not a primary study)

## What they did

The authors searched the medical literature and reviewed 12 controlled trials testing vitamin B6 for PMS, focusing on the quality of each study's methods.

## What they found

Some trials showed positive effects of vitamin B6, but the existing evidence is weak. A major problem is that most trials included too few patients.

## What it means for you

We cannot yet say whether vitamin B6 truly helps PMS because the studies so far have been too small and the results are not strong enough to be convincing. We would need larger, well-designed trials with clear positive results.

12 trials

Reviewed in this study

## About the study

Original title Vitamin B6 in the treatment of the premenstrual syndrome--a review Authors Kleijnen J, Ter Riet G, Knipschild P Journal British journal of obstetrics and gynaecology Year 1990 Study design Randomised trial What was tested Vitamin B6 Read the paper [doi.org/10.1111/j.1471-0528.1990.tb02582.x](https://doi.org/10.1111/j.1471-0528.1990.tb02582.x)

## Topics

[Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Vitamin B6](https://niyora.com/research/topics/treatment-vitamin-b6/)

Research tells you what helps on average. Niyora helps on the day it hits.

Calm down, see it another way, and decide what to say, with a PMS and PMDD app built by a doctor.

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